Background: Every day patient´s get isolated in hospitals as a consequense of infection control purposes. Physical isolation can result in lack of human contact and a new unknown environment for the patient. Those two factors can easily cause stress within the patient and create anxiety for the future. Aim: The aim of the study was to describe patient´s experience of being nursed in an isolation room. Method: The method that was used was a literature research, where earlier research findings were read and put together. Results: In most studies patient´s experience negative feelings such as depression, anxiety and other mood disturbances. Positive feelings like being alone was also described. Other categories that occurred was the need for information, the environment and contact with staff and relatives. Discussion: The nurse has a big influence on the patient´s experience and it´s important to have a close relationship with the patient. It´s also important that she can sit down quietly with the patient and have an open discussion regarding the patient´s care and give room for eventual questions. Through knowledge and understanding she can hopefully reduce the negative effects of isolation that might occur.