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  • 51.
    Baeshen, H.A.
    et al.
    Department of Cariology, Sahlgrenska Academy at University of Gothenburg.
    Kjellberg, H.
    Department of Orthodontics, Sahlgrenska Academy at University of Gothenburg.
    Lingström, Peter
    Högskolan Kristianstad, Institutionen för hälsovetenskaper.
    Birkhed, Dowen
    Department of Cariology, Sahlgrenska Academy at University of Gothenburg.
    Uptake and release of fluoride from fluoride-impregnated chewing sticks (miswaks) in vitro and in vivo2008Ingår i: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 42, nr 5, s. 363-368Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    The purpose was to investigate the uptake and release of fluoride (F) from F-impregnated chewing sticks (miswaks). In the first series, 3-cm-long pieces were impregnated in 1, 2, 3 and 4% NaF solutions for 3 h, 1 day and 3 days (10 pieces/test). There was a dose-response effect with respect to both impregnation time and the concentration of the F solution. In the second and third series, totally 40 miswak pieces were impregnated in 3% NaF for 1 day and 3 days; the outer layer (bark) was separated from the inner spongy part (pulp) and analyzed separately. F was released from both parts, but somewhat more was released from the bark than from the pulp; a plateau was reached at around 30 min. In vivo, 9 healthy subjects used three products for 2 min in a crossover design: (1) a miswak impregnated in 3% NaF for 1 day, (2) a miswak impregnated in 3% NaF for 3 days, and (3) 1 g of F toothpaste (containing 1,450 ppm F as NaF) on a toothbrush. The highest F concentration at the approximal area was obtained after using the miswak impregnated in 3% NaF for 3 days compared with the other products (p < 0.05 or p < 0.01). To conclude, NaF-impregnated miswaks produced a rapid release of F in vitro as well as in vivo and may be an interesting vehicle for home care use for caries prevention in countries where they are used regularly.

  • 52.
    Barbu, Sandra
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Dirland, Joy
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Undersköterskors uppfattning om oral hälsa och munvård på cancerpatienter: en kvalitativ studie2015Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med studien var att belysa undersköterskors uppfattning om oral hälsa ochmunvård som utförs på inneliggande cancerpatienter.En kvalitativ studie har tillämpats med en intervjuguide som underlag. Åtta informanterintervjuades i anslutning till deras arbetsplats och intervjuerna varade 10-20 minuter.För att analysera intervjumaterialet användes en kvalitativ innehållsanalys.Resultatet redovisas utifrån temat ”oral hälsa hos cancerpatienter viktigt men lågtprioriterat”. Att hjälpa patienterna med den dagliga munhygienen, upplevde inteinformanterna som något obehagligt utan såg det som en självklar del i sin yrkesroll.Informanterna upplevde även att den orala hälsan inte prioriterade och att det var svårtatt utföra munvård när patienterna nekade hjälp.Studiens slutsats visar att informanterna uppfattar den orala hälsan som en viktig del förpatientens välbefinnande men att munvård inte är det första som prioriteras hoscancerpatienter.

  • 53.
    Bashara, Haitham
    et al.
    Dublin Dental School and Hospital, Division of Restorative Dentistry and Periodontology.
    Wohlfahrt, Johan Caspar
    Department of Biomaterials, University of Oslo.
    Polyzois, Ioannis
    Dublin Dental School and Hospital, Division of Restorative Dentistry and Periodontology.
    Lyngstadaas, Staale Petter
    Department of Biomaterials, University of Oslo.
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Claffey, Noel
    Dublin Dental School and Hospital, Division of Restorative Dentistry and Periodontology.
    The effect of permanent grafting materials on the preservation of the buccal bone plate after tooth extraction: an experimental study in the dog2012Ingår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 23, nr 8, s. 911-917Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives: The aim of the present study was to evaluate the effects of a novel bone substitute system (Natix®), consisting of porous titanium granules (PTG) and a bovine-derived xenograft (Bio-Oss®), on hard tissue remodelling following their placement into fresh extraction sockets in dogs. Material and methods: Six modalities were tested; Natix® granules with and without a covering double-layered Bio Gide® membrane; Bio-Oss® with and without a covering double-layered Bio Gide® membrane; and a socket left empty with and without a covering double-layered Bio Gide® membrane. Linear measurements, indicative of buccal bone height loss, and an area measurement indicative of buccal bulk bone loss were made. The statistical analysis was based on the Latin Square design with two blocking factors (dog and site). Tukey's post hoc test was used to adjust for multiple comparisons. Results: Histological observation revealed that while bone formed around both the xenograft and the titanium particles, bone was also noted within titanium granules. Of the five modalities of ridge preservation techniques used in this study, no one technique proved to be superior. Conclusion: The titanium granules were observed to have promising osseoconductive properties.

  • 54.
    Baumgartner, Stefan
    et al.
    University of Bern, Bern, Switzerland.
    Imfeld, Thomas
    University of Zürich, Zürich, Switzerland.
    Schicht, Olivier
    University of Zürich, Zürich, Switzerland.
    Rath, Christian
    University of Zürich, Zürich, Switzerland.
    Persson, Rigmor E
    University of Bern, Bern, Switzerland & University of Washington.
    Persson, G Rutger
    University of Bern, Bern, Switzerland & University of Washington.
    The impact of the stone age diet on gingival conditions in the absence of oral hygiene.2009Ingår i: Journal of Periodontology, ISSN 0022-3492, E-ISSN 1943-3670, Vol. 80, nr 5, s. 759-768Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: The objective of this study was to assess the oral microbiota and clinical data in subjects without access to traditional oral hygiene methods and who ate a diet available in the Stone Age.

    METHODS: Ten subjects living in an environment replicating the Stone Age for 4 weeks were enrolled in this study. Bleeding on probing (BOP), gingival and plaque indices, and probing depth (PD) were assessed at baseline and at 4 weeks. Microbiologic samples were collected at the mesio-buccal subgingival aspects of all teeth and from the dorsum of the tongue and were processed by checkerboard DNA-DNA hybridization methods.

    RESULTS: No subject had periodontitis. Mean BOP decreased from 34.8% to 12.6% (P <0.001). Mean gingival index scores changed from 0.38 to 0.43 (not statistically significant) and mean plaque scores increased from 0.68 to 1.47 (P <0.001). PD at sites of subgingival sampling decreased (mean difference: 0.2 mm; P <0.001). At week 4, the total bacterial count was higher (P <0.001) for 24 of 74 species, including Bacteroides ureolyticus, Eikenella corrodens, Lactobacillus acidophilus, Capnocytophaga ochracea, Escherichia coli, Fusobacterium nucleatum naviforme, Haemophilus influenzae, Helicobacter pylori, Porphyromonas endodontalis, Staphylococcus aureus (two strains), Streptococcus agalactiae, Streptococcus anginosis, and Streptococcus mitis. Bacterial counts from tongue samples were higher at baseline (P <0.001) for 20 species, including Tannerella forsythia (previously T. forsythensis), Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans; serotype a), and Streptococcus spp.

    CONCLUSIONS: The experimental gingivitis protocol is not applicable if the diet (e.g., Stone Age) does not include refined sugars. Although plaque levels increased, BOP and PD decreased. Subgingival bacterial counts increased for several species not linked to periodontitis, whereas tongue bacterial samples decreased during the study period.

  • 55. Benjasupattananan, Supranee
    et al.
    Lai, Caroline S Y
    Persson, G. Rutger
    University of Bern, Bern, Switzerland.
    Pjetursson, Bjarni E
    Lang, Niklaus P
    Effect of a stannous fluoride dentifrice on the sulcular microbiota: a prospective cohort study in subjects with various levels of periodontal inflammation2005Ingår i: Oral Health & Preventive Dentistry, ISSN 1602-1622, E-ISSN 1757-9996, Vol. 3, nr 4, s. 263-272Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVES: To assess the effects of an experimental 0.454% stannous fluoride (SnF2) dentifrice on the oral sulcular microbiota in patients with various stages of oral diseases using checkerboard DNA-DNA hybridization.

    MATERIAL AND METHODS: In the present one-month, single center, single product, prospective cohort trial, 37 adults (mean age 37.6) were assigned to one of four oral health condition cohorts with seven to 10 subjects each: 1. mild gingivitis, 2. marked generalized gingivitis to moderate periodontitis, 3. caries-prone and 4. treated moderate to advanced chronic periodontitis in supportive periodontal care. All four groups were asked to use the test dentifrice and a power toothbrush twice a day for one minute during a four-week test period. Before and after the trial period, Plaque Indices (PII, Silness and Löe, 1964) and Gingival Indices (GI, Löe and Silness, 1963) were recorded. Subgingival plaque samples were collected from all patients at Baseline, as well as after two and four weeks. These samples were analyzed for content of 40 bacterial species using checkerboard DNA-DNA hybridization.

    RESULTS: As a result of the only one minute brushing with the stannous fluoride dentifrice, the mean PII at Baseline was significantly lower (p < 0.05) from the mean PII at four weeks. No statistically significant differences were found between premolar and molar mean values. Moreover, no statistically significant differences were found between the mean GI at Baseline and at four weeks. The microbiological analysis showed that at baseline subjects in groups 2 and 4 had significantly higher bacterial loads of bacteria than groups 1, and 3 (i.e. A. actinomyctemcomitans P. gingivalis, T. forsythia, and T. denticola. Over the study period, the total bacterial load did not change in groups 2, 3 and 4. In groups 1 and 3, however, an increase in the loads of Streptococci spp. were noticed (p < 0.05) including S. mitis, S. intermedius, and S. sanguis (p < 0.01) suggesting an increase in the presence of early colonizing and health associated bacteria.

    CONCLUSION: One minute brushing with a 0.454% stannous fluoride dentifrice did--after four weeks--not affect the subgingival microbial profiles in patients with moderate periodontitis and treated moderate to advanced periodontitis. However, the sulcular microbial profiles of mild gingivitis and caries-prone patients were affected, indicating a shift towards a gingival health associated microbiota in the sulcular region of patients not affected by attachment loss. RUNNING HEAD: Effect of stannous fluoride on sulcular microbiota.

  • 56.
    Berglundh, Tord
    et al.
    University of Gothenburg.
    Armitage, Gary
    USA.
    Araujo, Mauricio G
    Brazil.
    Avila-Ortiz, Gustavo
    USA.
    Blanco, Juan
    Spain.
    Camargo, Paulo M
    USA.
    Chen, Stephen
    Australia.
    Cochran, David
    USA.
    Derks, Jan
    University of Gothenburg.
    Figuero, Elena
    Spain.
    Hämmerle, Christoph H F
    Switzerland.
    Heitz-Mayfield, Lisa J A
    Switzerland.
    Huynh-Ba, Guy
    USA.
    Iacono, Vincent
    USA.
    Koo, Ki-Tae
    South Korea.
    Lambert, France
    Belgium.
    McCauley, Laurie
    Belgium.
    Quirynen, Marc
    Belgium.
    Renvert, Stefan
    Högskolan Kristianstad, Fakulteten för hälsovetenskap, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL). Högskolan Kristianstad, Fakulteten för hälsovetenskap, Avdelningen för oral hälsa.
    Salvi, Giovanni E
    Switzerland.
    Schwarz, Frank
    Germany.
    Tarnow, Dennis
    USA.
    Tomasi, Cristiano
    University of Gothenburg.
    Wang, Hom-Lay
    USA.
    Zitzmann, Nicola
    Switzerland.
    Peri-implant diseases and conditions: consensus report of workgroup 4 of the 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions2018Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 45, nr S20, s. 286-291Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    A classification for peri-implant diseases and conditions was presented. Focused questions on the characteristics of peri-implant health, peri-implant mucositis, peri-implantitis, and soft- and hard-tissue deficiencies were addressed. Peri-implant health is characterized by the absence of erythema, bleeding on probing, swelling, and suppuration. It is not possible to define a range of probing depths compatible with health; Peri-implant health can exist around implants with reduced bone support. The main clinical characteristic of peri-implant mucositis is bleeding on gentle probing. Erythema, swelling, and/or suppuration may also be present. An increase in probing depth is often observed in the presence of peri-implant mucositis due to swelling or decrease in probing resistance. There is strong evidence from animal and human experimental studies that plaque is the etiological factor for peri-implant mucositis. Peri-implantitis is a plaque-associated pathological condition occurring in tissues around dental implants, characterized by inflammation in the peri-implant mucosa and subsequent progressive loss of supporting bone. Peri-implantitis sites exhibit clinical signs of inflammation, bleeding on probing, and/or suppuration, increased probing depths and/or recession of the mucosal margin in addition to radiographic bone loss. The evidence is equivocal regarding the effect of keratinized mucosa on the long-term health of the peri-implant tissue. It appears, however, that keratinized mucosa may have advantages regarding patient comfort and ease of plaque removal. Case definitions in day-to-day clinical practice and in epidemiological or disease-surveillance studies for peri-implant health, peri-implant mucositis, and peri-implantitis were introduced. The proposed case definitions should be viewed within the context that there is no generic implant and that there are numerous implant designs with different surface characteristics, surgical and loading protocols. It is recommended that the clinician obtain baseline radiographic and probing measurements following the completion of the implant-supported prosthesis.

  • 57.
    Bergström, Anna
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Johansson, Susanna
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Upplevelse av smärta och tandvårdsrädsla: hos patienter på Högskolan Kristianstads tandvårdsklinik2013Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med studien var att undersöka samband mellan upplevelse av tandvårdsrädsla och smärta hos patienter vid tandhygienistbehandling. Ytterligare ett syfte var att undersöka om det fanns samband mellan kön och ålder i relation till tandvårdsrädsla och smärta. Studien genomfördes med användning av enkäter på patienter som behandlades av tandhygieniststudenter på Högskolan i Kristianstad. I studien ingick 78 respondenter, varav 39 män och lika många kvinnor i åldrarna 21-81 år. Enkäten bestod av två delar. Den första delen bestod av Dental Hygienist Anxiety Scale (DHAS) som användes för att mäta tandvårdsrädsla. Det fanns också två frågor om kön och ålder. Andra delen bestod av Visual Analogue Scale (VAS) som användes för att mäta smärtupplevelsen under fem behandlingsmoment, tandstensborttagning, röntgen, injektion, fickdjupsmätning samt behandling i helhet. Resultatet visade en statistisk signifikant skillnad mellan upplevelsen av smärta och tandvårdsrädsla (p=0,000) samt smärta och tandvårdsrädsla relaterat till ålder (p=0,011) (p=0,002). Ingen statistisk signifikant skillnad sågs gällande smärta och tandvårdsrädsla i samband med kön (p=0,682) (p=0,064). Slutsatsen var att ett samband kunde ses mellan smärta och tandvårdsrädsla. Den yngre åldersgruppen upplevde högre grad av smärta och tandvårdsrädsla än den äldre gruppen. Ingen skillnad kunde ses mellan kvinnors och mäns upplevelser av smärta och tandvårdsrädsla.

  • 58.
    Bieri, Regina Alessandri
    et al.
    University of Bern.
    Adriaens, Laurence
    University of Bern.
    Spörri, Stefan
    State Hospital of Fribourg, Fribourg, Switzerland.
    Lang, Niklaus P
    The University of Hong Kong.
    Persson, G. Rutger
    University of Bern & University of Washington, Seattle, WA, USA .
    Gingival fluid cytokine expression and subgingival bacterial counts during pregnancy and postpartum: a case series.2013Ingår i: Clinical Oral Investigations, ISSN 1432-6981, E-ISSN 1436-3771, Vol. 17, nr 1, s. 19-28Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVES: The aim of this study was to assess gingival fluid (GCF) cytokine messenger RNA (mRNA) levels, subgingival bacteria, and clinical periodontal conditions during a normal pregnancy to postpartum.

    MATERIALS AND METHODS: Subgingival bacterial samples were analyzed with the checkerboard DNA-DNA hybridization method. GCF samples were assessed with real-time PCR including five proinflammatory cytokines and secretory leukocyte protease inhibitor.

    RESULTS: Nineteen pregnant women with a mean age of 32 years (S.D. ± 4 years, range 26-42) participated in the study. Full-mouth bleeding scores (BOP) decreased from an average of 41.2% (S.D. ± 18.6%) at the 12th week of pregnancy to 26.6% (S.D. ± 14.4%) at the 4-6 weeks postpartum (p < 0.001). Between week 12 and 4-6 weeks postpartum, the mean probing pocket depth changed from 2.4 mm (S.D. ± 0.4) to 2.3 mm (S.D. ± 0.3) (p = 0.34). Higher counts of Eubacterium saburreum, Parvimonas micra, Selenomonas noxia, and Staphylococcus aureus were found at week 12 of pregnancy than at the 4-6 weeks postpartum examinations (p < 0.001). During and after pregnancy, statistically significant correlations between BOP scores and bacterial counts were observed. BOP scores and GCF levels of selected cytokines were not related to each other and no differences in GCF levels of the cytokines were observed between samples from the 12th week of pregnancy to 4-6 weeks postpartum. Decreasing postpartum counts of Porphyromonas endodontalis and Pseudomonas aeruginosa were associated with decreasing levels of Il-8 and Il-1β.

    CONCLUSIONS: BOP decreased after pregnancy without any active periodontal therapy. Associations between bacterial counts and cytokine levels varied greatly in pregnant women with gingivitis and a normal pregnancy outcome. Postpartum associations between GCF cytokines and bacterial counts were more consistent.

    CLINICAL RELEVANCE: Combined assessments of gingival fluid cytokines and subgingival bacteria may provide important information on host response.

  • 59.
    Bile-Samatar, Suad
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Patel, Hina
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Orala problem vid Parkinsons sjukdom2013Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Parkinsons sjukdom är en progressiv degenerativ neurologisk sjukdom. I Sverige finns det 15 000–20 000 personer som är drabbade av sjukdomen.

    Syftet med litteraturstudien var att undersöka förekomsten av orala problem vid Parkinsons sjukdom.

    Materialet till litteraturstudien söktes i den medicinska databasen PubMed, där sökorden var ”Parkinson’s disease”, “oral diseases”, “dry mouth”, ”gingivitis”, “caries” och “periodontitis”. Resultatet baseras på en sammanställning av elva vetenskapliga artiklar som har granskats och analyserats. Åtta artiklar var kontrollerade kliniska studier. En artikel undersökte munhälsan kliniskt och självupplevd oral hälsa. Två artiklar undersökte den självupplevda orala hälsan varav en hade en kontrollgrupp.   

    Resultatet visade att Parkinsonsjuka hade mer gingivit och att prevalensen av parodontit var statistisk signifikant högre hos Parkinsonsjuka än hos en kontrollgrupp. Obehandlad karies och lägre salivflöde förekom mer hos Parkinsonsjuka än icke Parkinsonsjuka.

    Slutsatsen i litteraturstudien är att Parkinsonsjuka har sämre munhälsa än icke Parkinsonsjuka.

  • 60.
    Bordbar, Kaveh
    Högskolan Kristianstad, Sektionen för Hälsa och Samhälle.
    Kunskap om och upplevelse av halitosis samt klinisk mätning av svavelhaltiga gaser bland gymnasieelever2010Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med denna studie var att undersöka kunskapen och upplevelsen av dålig andedräkt hos gymnasieelever i Kristianstad, ytterligare ett syfte var att mäta mängden VSC (reaktiva svavelföreningar)  hos dem som upplever sig ha dålig andedräkt. En enkät med 21 slutna frågor delades ut till 120 gymnasieelever som var mellan 17-20 år och studerade i Kristanstads kommun. Av resultatet i denna studie framkom att de flesta av gymnasieeleverna hade goda kunskaper om halitosis. Nästan alla 120 som besvarade enkäten tyckte att det var viktigt att lukta fräsch i munnen och dessutom upplevde de flesta sin andedräkt som mycket bra eller bra. Endast ett fåtal (14% ) kände att de ibland hade dålig andedräkt. Hos dessa  påverkades inte andedräkten deras vardagliga liv och de hade aldrig blivit generade eller hamnat i pinsamma situationer på grund av sin andedräkt. Resultatet från den kliniska undersökningen som gjordes på 8 av de 120 elever som besvarade enkäten där mängden av de svavelhaltiga gaserna i munhålan mättes visade att i genomsnitt ligger värden som framkom i undersökningen under gränsvärden för att man skall ha dålig andedräkt.

  • 61.
    Bornstein, Michael M
    et al.
    University of Bern, Bern, Switzerland.
    Hakimi, Basir
    University of Bern, Bern, Switzerland.
    Persson, G. Rutger
    University of Bern, Bern, Switzerland & University of Washington, Seattle, WA.
    Microbiological findings in subjects with asymptomatic oral lichen planus: a cross-sectional comparative study.2008Ingår i: Journal of Periodontology, ISSN 0022-3492, E-ISSN 1943-3670, Vol. 79, nr 12, s. 2347-2355Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: The bacterial colonization of the oral mucosa was evaluated in patients with asymptomatic oral lichen planus (OLP) and compared to the microbiologic status in mucosally healthy subjects.

    METHODS: Bacteria from patients with clinically and histopathologically diagnosed OLP from the Stomatology Service, Department of Oral Surgery and Stomatology, School of Dental Medicine, University of Bern, were collected with a non-invasive swab system. Samples were taken from OLP lesions on the gingiva and from non-affected sites on the contralateral side of the mouth. The control population did not have OLP and was recruited from the student clinic. All samples were processed with the checkerboard DNA-DNA hybridization method using well-defined bacterial species for the analysis.

    RESULTS: Significantly higher bacterial counts of Bacteroides ureolyticus (P = 0.001), Dialister species (sp.) (P = 0.006), Staphylococcus haemolyticus (P = 0.007), and Streptococcus agalactiae (P = 0.006) were found in samples taken from OLP lesions compared to sites with no clinical evidence of OLP. Significantly higher bacterial counts were found for Capnocytophaga sputigena, Eikenella corrodens, Lactobacillus crispatus, Mobiluncus curtisii, Neisseria mucosa, Prevotella bivia, Prevotella intermedia, and S. agalactiae at sites with lesions in subjects with OLP compared to sites in control subjects (P <0.001).

    CONCLUSIONS: Microbiologic differences were found between sites with OLP and sites in subjects without a diagnosis of OLP. Specifically, higher counts of staphylococci and S. agalactiae were found in OLP lesions.

  • 62.
    Brito, Fernanda
    et al.
    Univ Estado Rio De Janeiro, Fac Odontol, Dept Periodontol, BR-20551030 Rio De Janeiro, Brazil.
    Zaltman, Cyrla
    Univ Fed Rio de Janeiro, Fac Med, Dept Gastroenterol, Rio De Janeiro, Brazil.
    Carvalho, Ana T P
    Univ Estado Rio De Janeiro, Fac Med, Dept Gastroenterol, BR-20551030 Rio De Janeiro, Brazil.
    Fischer, Ricardo G
    Univ Estado Rio De Janeiro, Fac Odontol, Dept Periodontol, BR-20551030 Rio De Janeiro, Brazil.
    Persson, G. Rutger
    Univ Bern, Sch Dent Med, Dept Periodontol, Bern, Switzerland & Univ Washington, Sch Dent, Dept Oral Med, Seattle, WA 98195 USA.
    Gustafsson, Anders
    Karolinska Inst, Div Perisodontol, Dept Dent Med, Stockholm, Sweden.
    Figueredo, Carlos M S
    Univ Estado Rio De Janeiro, Fac Odontol, Dept Periodontol, BR-20551030 Rio De Janeiro, Brazil & Karolinska Inst, Div Perisodontol, Dept Dent Med, Stockholm, Sweden.
    Subgingival microflora in inflammatory bowel disease patients with untreated periodontitis.2013Ingår i: European Journal of Gastroenterology and Hepathology, ISSN 0954-691X, E-ISSN 1473-5687, Vol. 25, nr 2, s. 239-245Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVE: To analyze the subgingival microflora composition of inflammatory bowel disease (IBD) patients with untreated chronic periodontitis and compare them with systemically healthy controls also having untreated chronic periodontitis.

    METHOD: Thirty IBD patients [15 with Crohn's disease (CD) and 15 with ulcerative colitis (UC)] and 15 control individuals participated in the study. All patients had been diagnosed with untreated chronic periodontitis. From every patient, subgingival plaque was collected from four gingivitis and four periodontitis sites with paper points. Samples from the same category (gingivitis or periodontitis) in each patient were pooled together and stored at -70 °C until analysis using a checkerboard DNA-DNA hybridization technique for 74 bacterial species.

    RESULTS: Multiple-comparison analysis showed that the groups differed in bacterial counts for Bacteroides ureolyticus, Campylobacter gracilis, Parvimonas micra, Prevotella melaninogenica, Peptostreptococcus anaerobius, Staphylococcus aureus, Streptococcus anginosus, Streptococcus intermedius, Streptococcus mitis, Streptococcus mutans, and Treponema denticola (P<0.001). CD patients had significantly higher levels of these bacteria than UC patients either in gingivitis or in periodontitis sites (P<0.05). CD patients harbored higher levels of P. melaninogenica, S. aureus, S. anginosus, and S. mutans compared with controls both at gingivitis and at periodontitis sites (P<0.05). UC patients harbored higher levels of S. aureus (P=0.01) and P. anaerobius (P=0.05) than controls only in gingivitis sites.

    CONCLUSION: Our study showed that even with similar clinical periodontal parameters, IBD patients harbor higher levels of bacteria that are related to opportunistic infections in inflamed subgingival sites that might be harmful for the crucial microbe-host interaction.

  • 63.
    Changpook, Sakulket
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Gieng, My
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Patienters upplevelser av besök på studentkliniken, Tandhygienistprogrammet Högskolan Kristianstad2017Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med studien var att beskriva hur patienter upplevde bemötande och kommunikation vid besök på studentkliniken, Högskolan Kristianstad. En kvalitativ studie genomfördes med användning av en intervjuguide. Åtta patienter intervjuades med hjälp av en digital diktafon och varade i cirka 30 minuter. En kvalitativ innehållsanalys tillämpades för analys av insamlad data. Resultatet visade att patienterna upplevde ett gott och vänligt bemötande när tandhygieniststudenterna, handledarna och personalen i receptionen hälsade på dem. Patienterna upplevde en god kommunikation och ansåg bland annat att de var delaktiga i konversationen och fick en begriplig information. Det som upplevdes mindre bra var att viss information under behandlingen var tjatig och att en patient inte upplevde sig ha en dialog när handledaren pratade med studenten. Slutsatsen av studien visar att samtliga patienter upplever ett gott bemötande på studentkliniken och att majoriteten upplever att kommunikationen är positiv. 

  • 64.
    Chen, Jenny
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Milton, Lisa
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Oral Health and the Effect on Quality of Life in a Zambian population2012Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med studien var att undersöka hur den orala hälsan påverkar livskvalitéten bland patienter som besökte en tandklinik i Livingstone samt på kliniken vid Dental training school i Lusaka, Zambia. Sammanlagt 160 patienter valdes konsekutivt ut och var i åldrarna 16-68 år (32 ± 11,8; medel ± SD). Studien utfördes genom intervjuer med hjälp av en enkät, ”The Oral Impacts on Daily Performances” (OIDP). Av patienterna svarade 80% att de blev påverkade av deras orala hälsa med minst ett problem. Svårigheter med att ”äta och njuta av mat” var det vanligaste problemet (54%) medan ”att tala och ha bra uttal” var det problem som var minst rapporterat (16%). Överlag, rapporterade 20% att de inte hade några problem alls. När de rapporterade att de hade problem var det vanligaste 3 och 4 antal problem. Två öppna frågor ställdes, ”Varför kom du till kliniken” och ”Vad tror du är problemet”. Det vanligaste svaret på första frågan var ”smärta” (38.9%) och på andra frågan ”vet inte” (23.1%). Denna studie kom fram till att 80% tyckte att deras orala hälsa påverkade deras liv och livskvalité.

  • 65. Chung, Whasun O
    et al.
    Gabany, Joseph
    Persson, G. Rutger
    University of Washington, Seattle, WA, USA.
    Roberts, Marilyn C
    Distribution of erm(F) and tet(Q) genes in 4 oral bacterial species and genotypic variation between resistant and susceptible isolates.2002Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 29, nr 2, s. 152-158Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Bacteroides forsythus, Porphyromonas gingivalis and Prevotella intermedia are Gram-negative anaerobic bacteria that are currently considered potential periopathogens. Prevotella nigrescens has recently been separated from P. intermedia and its rôle in periodontitis is unknown. The erm(F) gene codes for an rRNA methylase, conferring resistance to macrolides, lincosamides and streptogramin B (MLSB), and the tet(Q) gene for a ribosomal protection protein, conferring resistance to tetracycline. The presence of these resistance genes could impair the use of antibiotics for therapy.

    PURPOSE: The aim of this study was to determine the carriage of erm(F) and tet(Q), and genetic variability of 12 Porphyromonas gingivalis, 10 Prevotella intermedia, 25 Prevotella nigrescens and 17 Bacteroides forsythus isolates from 9 different patient samples.

    METHODS: We used polymerase chain reaction (PCR) for detecting antibiotic resistance genes, and pulsed-field gel electrophoresis (PFGE) for detecting genetic variability among the isolates.

    RESULTS: Thirty-one (48%) isolates were resistant to both erythromycin and tetracycline and carried the erm(F) and tet(Q) genes, eight (13%) were tetracycline resistant and carried the tet(Q) gene, 9 (14%) were erythromycin resistant and carried the erm(F) gene, and 12 (19%) isolates did not carry antibiotic resistance genes. PFGE was used to compare isolates from the same patient and isolates from different patient samples digested with XbaI. No association was found between antibiotic resistance gene carriage and PFGE patterns in any species examined. All isolates of the same species from the same patient had highly related or identical PFGE patterns. Isolates of same species from different patients had unique PFGE pattern for each species tested.

    CONCLUSION: All isolates of the same species from any one patient were genetically related to each other but distinct from isolates from other patients, and 66% of the patients carried antibiotic resistant isolates, which could impair antibiotic therapy.

  • 66.
    Claffey, Noel
    et al.
    School of Dental Sciences, Trinity College, Dublin, Ireland.
    Clarke, Emily
    School of Dental Sciences, Trinity College, Dublin, Ireland.
    Polyzois, Ioannis
    School of Dental Sciences, Trinity College, Dublin, Ireland.
    Renvert, Stefan
    Högskolan Kristianstad, Institutionen för hälsovetenskaper.
    Surgical treatment of peri-implantitis2008Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 35, nr 8 Suppl, s. 316-32Artikel, forskningsöversikt (Övrigt vetenskapligt)
    Abstract [en]

    OBJECTIVES: To review the literature on surgical treatment of peri-implantitis. MATERIAL AND METHODS: A search of PubMed and as well as a hand search of articles were conducted. Publications and articles accepted for publication up to November 2007 were included. RESULTS: A total of 43 studies were selected for the review. Only 13 of these were studies in humans and only one study directly addressed disease resolution. Thus the available evidence for surgical treatment of peri-implantitis is extremely limited. ANIMAL STUDIES: Re-osseointegration can occur on previously contaminated surfaces. The surface characteristics are decisive for regeneration and re-osseointegration. No single surface decontamination method appears to be distinctly superior. Open debridement with surface decontamination can achieve resolution. HUMAN STUDIES: Access surgery has been investigated in one study demonstrating that resolution occurred in 58% of the lesions. No single method of surface decontamination (chemical agents, air abrasives and lasers) was found to be superior. The use of regenerative procedures such as bone graft techniques with or without the use of barrier membranes has been reported with various degrees of success. However, it must be stressed that such techniques do not address disease resolution but rather merely attempt to fill the osseous defect.

  • 67.
    Cosyn, Jan
    et al.
    University of Ghent, Ghent, Belgium.
    Van Aelst, Louis
    University of Ghent, Ghent, Belgium.
    Collaert, Bruno
    Persson, G. Rutger
    Division of Oral Microbiology, University of Berne, Department of Periodontology, Berne, Switzerland, and Department of Periodontics, University of Washington, Seattle, WA, USA.
    De Bruyn, Hugo
    University of Ghent, Ghent, Belgium.
    The peri-implant sulcus compared with internal implant and suprastructure components: a microbiological analysis.2011Ingår i: Clinical Implant Dentistry and Related Research, ISSN 1523-0899, E-ISSN 1708-8208, Vol. 13, nr 4, s. 286-295Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    PURPOSE: A recent in vivo study has shown considerable contamination of internal implant and suprastructure components with great biodiversity, indicating bacterial leakage along the implant-abutment interface, abutment-prosthesis interface, and restorative margins. The goal of the present study was to compare microbiologically the peri-implant sulcus to these internal components on implants with no clinical signs of peri-implantitis and in function for many years. Checkerboard DNA-DNA hybridization was used to identify and quantify 40 species.

    MATERIAL AND METHODS: Fifty-eight turned titanium Brånemark implants in eight systemically healthy patients (seven women, one man) under regular supportive care were examined. All implants had been placed in the maxilla and loaded with a screw-retained full-arch bridge for an average of 9.6 years. Gingival fluid samples were collected from the deepest sulcus per implant for microbiological analysis. As all fixed restorations were removed, the cotton pellet enclosed in the intra-coronal compartment and the abutment screw were retrieved and microbiologically evaluated.

    RESULTS: The pellet enclosed in the suprastructure was very similar to the peri-implant sulcus in terms of bacterial detection frequencies and levels for practically all the species included in the panel. Yet, there was virtually no microbial link between these compartments. When comparing the abutment screw to the peri-implant sulcus, the majority of the species were less frequently found, and in lower numbers at the former. However, a relevant link in counts for a lot of bacteria was described between these compartments. Even though all implants in the present study showed no clinical signs of peri-implantitis, the high prevalence of numerous species associated with pathology was striking.

    CONCLUSIONS: Intra-coronal compartments of screw-retained fixed restorations were heavily contaminated. The restorative margin may have been the principal pathway for bacterial leakage. Contamination of abutment screws most likely occurred from the peri-implant sulcus via the implant-abutment interface and abutment-prosthesis interface.

  • 68.
    Czarnecka, Anna
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Khadhem, Rownak
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Rökares självupplevda orala hälsa samt uppfattning om rökningens påverkan på oral hälsa2015Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Bakgrund: Oral hälsa definieras som ett tillstånd där individen är fri från orala sjukdomar samt störningar som påverkar munhålan negativt. Inom tandvården har oral hälsa länge setts utifrån ett biologiskt synsätt. Idag inriktas den på ett mer holistiskt synsätt som innefattar en individs välbefinnande och upplevelse av den egna orala hälsan.

    Syfte: Syftet med studien var att belysa rökarens självupplevda orala hälsa samt uppfattning om rökningens påverkan på den orala hälsan.

    Metod: En kvalitativ studie genomfördes med intervjuer som datainsamling. Åtta rökare i åldrarna 27-65 inkluderades. Inklusionskriterier var rökare som hade rökt i minst fem år, minst fem cigaretter dagligen och som kunde uttrycka sig på svenska.

    Resultat: Samtliga informanter upplevde obehag och orala besvär i munnen som hade en påverkan på deras välbefinnande. Obehagen kunde upplevas som muntorrhet, dålig andedräkt samt missfärgningar. Orala besvär upplevdes som karies, blottlagda tandhalsar och tandköttsinflammation. Informanterna uppfattade också att rökning hade konsekvenser på den orala hälsan. Vissa informanter hade inte tillräckligt med kunskaper om hur rökning påverkade den orala hälsan.

    Slutsats: Informanterna upplevde obehag och orala besvär i munnen och att det hade en påverkan på deras välbefinnande. Studien visade även att informanterna uppfattade att rökning hade en påverkan på den orala hälsan.

  • 69.
    Dahl, Malin
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Ljunggren, Elin
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Boendeassistenters kunskap om munhälsa och inställning till munvård2014Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Introduktion: Personer med funktionsnedsättning har nedsatt förmåga att fungera fysiskt, psykiskt eller intellektuellt, vilket kan medföra hinder med att sköta den dagliga munhygienen. I omvårdnaden i bostad med särskild service för vuxna ingår skyldighet att stödja funktionsnedsatta med deras personliga behov.

    Syfte: Syftet med studien var att undersöka boendeassistenters kunskap om munhälsa. Ytterligare ett syfte var att undersöka boendeassistenters inställning till munvård samt faktorer som påverkar deras inställning till munvård.

    Material och metod: Studien är en kvantitativ tvärsnittstudie baserad på en enkät med 31 strukturerade frågor samt en öppen fråga.  Enkäten besvarades av 43 boendeassistenter i en kommun i södra Sverige.

    Resultat: Resultatet visar att majoriteten (n=34) av boendeassistenterna anser att de boende behöver dagligt stöd med munhygienen. Det största hindret är att de boende inte vill ha hjälp med munhygienen. En stor del (n=31) av boendeassistenterna anser att de har tillräcklig kunskap om munvård för att stödja de boende med den dagliga munhygienen. Resultatet visar att 29 av boendeassistenterna har kunskap om fluor och 38 har kunskap om gingivit.

    Slutsats: Resultatet tyder på att boendeassistenterna i viss mån har kunskap om munhälsa och att de anser att de boende behöver dagligt stöd med munvården. Vidare anser boendeassistenterna att det största hindret till att stödja med munvården är att de boende inte vill ha hjälp vilket påverkar boendeassistenternas inställning till munvård.

  • 70.
    Dalago, Haline Renata
    et al.
    Brasilien.
    Schuldt Filho, Guenther
    Brasilien.
    Rodrigues, Mônica Abreu Pessoa
    Brasilien.
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL).
    Bianchini, Marco Aurélio
    Brasilien.
    Risk indicators for peri-implantitis: a cross-sectional study with 916 implants2017Ingår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 28, nr 2, s. 144-150Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVES: The aim of this study was to identify systemic and local risk indicators associated with peri-implantitis.

    MATERIAL AND METHODS: One hundred eighty-three patients treated with 916 osseointegrated titanium implants, in function for at least 1 year, were included in the present study. The implants were installed at the Foundation for Scientific and Technological Development of Dentistry (FUNDECTO) - University of Sao Paulo (USP) - from 1998 to 2012. Factors related to patient's systemic conditions (heart disorders, hypertension, smoking habits, alcoholism, liver disorders, hepatitis, gastrointestinal disease, diabetes mellitus I and II, hyperthyroidism or hypothyroidism, radiation therapy, chemotherapy, menopause, osteoporosis, active periodontal disease, history of periodontal disease and bruxism), implant's characteristics (location, diameter, length, connection, shape, and antagonist), and clinical parameters (wear facets, periodontal status on the adjacent tooth, plaque accumulation on the adjacent tooth, modified plaque index, sulcus bleeding index, probing depth, bleeding on probing, width of keratinized tissue and marginal recession).

    RESULTS: An increased risk of 2.2 times for history of periodontal disease (PD), 3.6 times for cemented restorations compared to screw-retained prostheses, 2.4 times when wear facets were displayed on the prosthetic crown and 16.1 times for total rehabilitations when compared to single rehabilitations were found. Logistic regression analysis did not show any association between the implant's characteristics and peri-implantitis.

    CONCLUSIONS: A history of periodontal disease, cemented prostheses, presences of wear facets on the prosthetic crown and full mouth rehabilitations were identified as risk indicators for peri-implantitis. Implants' characteristics were not related to the presence of peri-implantitis.

  • 71.
    Dalum, Jesper
    et al.
    Högskolan Kristianstad, Sektionen för Hälsa och Samhälle.
    Lennartsson, Joel
    Högskolan Kristianstad, Sektionen för Hälsa och Samhälle.
    Knowledge, management and self-perception of oral health among students attending the University of Dar es Salaam2011Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med studien var att undersöka kunskapen om, skötseln av och självuppfattningen om den orala hälsan bland studenter på University of Dar es Salaam, Tanzania. I studien ingick 273 studenter som studerade till lärare, en enkät användes för att samla in data.

    Resultatet visade att 153 (58%) av studenterna uppgav att syftet med fluor var att förebygga karies. Majoriteten svarade att bakteriers och sockers relation till bildandet av karies var betydelsefull. Studenterna uppgav att skolan var den största källan till träning i oral hälsa. Tandborste användes som främsta hjälpmedel för att rengöra tänderna och användning av fluortandkräm var ganska hög bland studenterna. Etthundrafyrtionio (55%) av deltagarna uppgav att de var i behov av tandvård och nittiotvå (34%) att den orala hälsan gav upphov till att livet i allmänhet var mindre tillfredställande. Studiens slutsats är att studenterna hade ganska god kunskap om sjukdomar i munhålan och dess prevention men det fanns kunskapsbrister kring bakomliggande faktorer. Skötseln av den oral hälsa tros vara god. Trots detta uppgav ganska många av de studerande att de hade behov av tandvård, hade känt att livet var mindre tillfredsställande på grund av problem i munhålan och hade orala problem som påverkade det dagliga livet.

  • 72. De Bruyn, Hugo
    et al.
    Bouvry, Peter
    Collaert, Bruno
    De Clercq, Calix
    Persson, G. Rutger
    University of Berne, Department of Periodontology, Division of Oral Microbiology, Berne, Switzerland; and University of Washington, Department of Periodontics, Seattle, WA, USA.
    Cosyn, Jan
    Long-term clinical, microbiological, and radiographic outcomes of Brånemark™ implants installed in augmented maxillary bone for fixed full-arch rehabilitation.2013Ingår i: Clinical Implant Dentistry and Related Research, ISSN 1523-0899, E-ISSN 1708-8208, Vol. 15, nr 1, s. 73-82Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    PURPOSE: The purpose of this study was to document the long-term outcome of Brånemark implants installed in augmented maxillary bone and to identify parameters that are associated with peri-implant bone level.

    MATERIAL AND METHODS: Patients of a periodontal practice who had been referred to a maxillofacial surgeon for iliac crest bone grafting in the atrophic maxilla were retrospectively recruited. Five months following grafting, they received 7-8 turned Brånemark implants. Following submerged healing of another 5 months, implants were uncovered and restorative procedures for fixed rehabilitation were initiated 2-3 months thereafter. The primary outcome variable was bone level defined as the distance from the implant-abutment interface to the first visible bone-to-implant contact. Secondary outcome variables included plaque index, bleeding index, probing depth, and levels of 40 species in subgingival plaque samples as identified by means of checkerboard DNA-DNA hybridization.

    RESULTS: Nine out of 16 patients (eight females, one male; mean age 59) with 71 implants agreed to come in for evaluation after on average 9 years (SD 4; range 3-13) of function. One implant was deemed mobile at the time of inspection. Clinical conditions were acceptable with 11% of the implants showing pockets ≥ 5 mm. Periodontopathogens were encountered frequently and in high numbers. Clinical parameters and bacterial levels were highly patient dependent. The mean bone level was 2.30 mm (SD 1.53; range 0.00-6.95), with 23% of the implants demonstrating advanced resorption (bone level > 3 mm). Regression analysis showed a significant association of the patient (p < .001) and plaque index (p = .007) with bone level.

    CONCLUSIONS: The long-term outcome of Brånemark implants installed in iliac crest-augmented maxillary bone is acceptable; however, advanced peri-implant bone loss is rather common and indicative of graft resorption. This phenomenon is patient dependent and seems also associated with oral hygiene.

  • 73.
    Dierens, Melissa
    et al.
    University of Ghent, Ghent, Belgium.
    Vandeweghe, Stefan
    University of Ghent, Ghent, Belgium & Malmö University, Malmö, Sweden.
    Kisch, Jenö
    Clinic for Prosthodontics, Centre of Dental Specialist Care, Malmö, Sweden.
    Persson, G. Rutger
    Department of Periodontology, University of Bern, Bern, Switzerland.
    Cosyn, Jan
    University of Ghent, Ghent, Belgium & Dental Medicine, Free University of Brussels (VUB), Brussels, Belgium.
    De Bruyn, Hugo
    University of Ghent, Ghent, Belgium & Malmö University, Malmö, Sweden.
    Long-term follow-up of turned single implants placed in periodontally healthy patients after 16 to 22 years: microbiologic outcome.2013Ingår i: Journal of periodontology, ISSN 1943-3670, Vol. 84, nr 7, s. 880-894Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Survival rates in implant dentistry today are high, although late failures do occur for many reasons, including peri-implant infections. The primary objective of this study is to investigate microbiota around single turned implants after 16 to 22 years. Secondary objectives are to compare teeth and implants and to correlate microbiologic, radiographic, and clinical parameters.

    METHODS: A total of 46 patients with single implants were invited for a clinical examination. Clinical data were collected from implants and contralateral natural teeth. Radiographic bone level was measured around implants. Microbiologic samples were taken from implants, contralateral teeth, and the deepest pocket per quadrant. Samples were analyzed with DNA-DNA hybridization including 40 species. Statistical analysis was performed using Wilcoxon signed-rank tests, McNemar tests, and Spearman correlation coefficients with a 0.05 significance level.

    RESULTS: Mean follow-up was 18.5 years (range 16 to 22 years). Tannerella forsythia (1.5 × 10(5)) and Veillonella parvula (1.02 × 10(5)) showed the highest concentrations around implants and teeth, respectively. Porphyromonas gingivalis, Prevotella intermedia, and T. forsythia were significantly more present around implants than teeth. Mean counts were significantly higher around implants than teeth for Parvimonas micra, P. gingivalis, P. intermedia, T. forsythia, and Treponema denticola. Total DNA count was correlated to interproximal bleeding index (r = 0.409) and interproximal probing depth (r = 0.307). No correlations were present with plaque index or radiographic bone level.

    CONCLUSIONS: In the present study, bacterial counts around single implants in periodontally healthy patients are rather low. Although pathogenic bacteria are present, some in higher numbers around implants than teeth (five of 40), the majority of implants present with healthy peri-implant tissues without progressive bone loss.

  • 74.
    Duncan, W J
    et al.
    University of Otago, Dunedin, New Zealand.
    Persson, G. Rutger
    University of Washington, Seattle, WA, USA.
    Sims, T J
    University of Washington, Seattle, WA, USA.
    Braham, P
    University of Washington, Seattle, WA, USA.
    Pack, A R C
    University of Otago, Dunedin, New Zealand.
    Page, R C
    University of Washington, Seattle, WA, USA.
    Ovine periodontitis as a potential model for periodontal studies. Cross-sectional analysis of clinical, microbiological, and serum immunological parameters.2003Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 30, nr 1, s. 63-72Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    OBJECTIVES: : To investigate infection and host immunity patterns in sheep with naturally occurring "broken-mouth" periodontitis.

    MATERIALS AND METHODS: : Eight periodontally healthy (HS) and eight periodontally diseased ewes (PDS) were selected. Subgingival plaque and sera were collected and examined for evidence of human periodontitis-associated pathogens. Serum IgG titers were measured by ELISA to multiple strains of Porphyromonas gingivalis, Bacteroides forsythus, Dichelobacter nodosus, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Fusobacterium nucleatum as well as several purified antigens (cysteine proteases, LPS, K, and fimbriae).

    RESULTS: : Neither the organism Aa nor antigens to Aa were found in any animal. Most animals were positive for Pg, Bf, and Pi, but DNA probes detected no difference between HS and PDS relative to amounts of pathogens in subgingival plaque. PDS had significantly higher serum IgG titers to all Pg strains, to 50% of Bf strains, to the Pi and Fn strains, and to fimbriae and the two cysteine proteases (p-values ranging from 0.05 to 0.001). Regression analysis demonstrated a significant association between number of teeth lost and serum IgG antibody titers to whole-cell sonicate antigens of P. gingivalis strains (p<0.01) and body weight (p<0.01).

    CONCLUSIONS: : The presence of pathogens associated with periodontitis was reflected in differences in serum IgG titers between healthy and diseased sheep. This may have influenced animal body weight and might have systemic health and economic consequences. The data suggest that susceptible and non-susceptible sheep can be identified for periodontal research.

  • 75.
    Duss, Christof
    et al.
    Department of Periodontology, Faculty of Medicine, University of Berne.
    Lang, Niklaus P.
    Department of Periodontology, Faculty of Medicine, University of Berne.
    Cosyn, Jan
    Department of Dentistry, University of Ghent.
    Persson, G. Rutger
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    A randomized, controlled clinical trial on the clinical, microbiological, and staining effects of a novel 0.05% chlorhexidine/herbal extract and a 0.1% chlorhexidine mouthrinse adjunct to periodontal surgery2010Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 37, nr 11, s. 988-997Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background Chlorhexidine (CHX) rinsing after periodontal surgery is common. We assessed the clinical and microbiological effects of two CHX concentrations following periodontal surgery. Materials and methods In a randomized, controlled clinical trial, 45 subjects were assigned to 4 weeks rinsing with a 0.05 CHX/herbal extract combination (test) or a 0.1% CHX solution. Clinical and staining effects were studied. Subgingival bacteria were assessed using the DNA-DNA checkerboard. Statistics included parametric and non-parametric tests (p < 0001 to declare significance at 80% power). Results At weeks 4 and 12, more staining was found in the control group (p < 0.05 and p < 0.001, respectively). A higher risk for staining was found in the control group (crude OR: 2.3:1, 95% CI: 1.3 to 4.4, p < 0.01). The absolute staining reduction in the test group was 21.1% (9 5% CI: 9.4-32.8%). Probing pocket depth (PPD) decreases were significant (p < 0.001) in both groups and similar (p=0.92). No rinse group differences in changes of bacterial counts for any species were found between baseline and week 12. Conclusions The test CHX rinse resulted in less tooth staining. At the study endpoint, similar and high counts of periodontal pathogens were found.

  • 76. Dörtbudak, Orhun
    et al.
    Eberhardt, Rita
    Ulm, Martin
    Persson, G. Rutger
    University of Bern, Switzerland & University of Washington, Seattle, WA, USA.
    Periodontitis, a marker of risk in pregnancy for preterm birth.2005Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 32, nr 1, s. 45-52Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Why chronic periodontitis may induce an inflammatory response with premature pregnancy termination is unclear.

    AIMS: (1) To assess if periodontitis predicts premature gestation; (2) to study amniotic fluid cytokines and periodontitis variables in early-stage pregnancy.

    MATERIAL AND METHODS: A periodontal examination and collection of amniotic fluid was performed (weeks 15-20) of pregnancy in 36 women at risk for pregnancy complications. Amniotic fluid (bacteria), vaginal smears and intra-oral plaque samples were studied. Cytokine levels in amniotic fluid were studied in relation to other study variables.

    RESULTS: Periodontitis was diagnosed in 20% of normal and in 83% of preterm birth cases (p<0.01). Bacteria were never found in the amniotic fluids studied. Sub-gingival plaque samples including bacteria in the orange and red complexes were found in 18% of full-term 100% of preterm cases (p<0.001) and total colony-forming units (CFUs) were higher in preterm birth (p<0.01). Amniotic levels of interleukin (IL)-6 and prostaglandin-E2 (PGE2) were higher in preterm cases (p<0.001). Amniotic IL-6 (r=0.56, p<0.01) and PGE2 (r=0.50, p<0.01) cytokine levels were correlated with CFU from sub-gingival plaque samples (r2=0.44). The odds ratio of preterm delivery and having periodontitis was 20.0 (95% confidence interval (CI): 2.0-201.7, p<0.01). The odds of >60 CFU in sub-gingival plaque and preterm birth was 32.5:1 (95% CI: 3.0-335.1, p<01).

    CONCLUSIONS: Pregnant women with findings of elevated amniotic fluid levels of PGE2, IL-6 and IL-8 in the 15-20 weeks of pregnancy and with periodontitis are at high risk for premature birth. The implication of this is that periodontitis can induce a primary host response in the chorioamnion leading to preterm birth.

  • 77.
    Edström, Emma
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Oliveira Santos, Késia
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Anestesianvändning vid depuration utförd av tandhygienister2015Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med studien var att kartlägga anestesianvändning vid depuration utförd av tandhygienister. Ett ytterligare syfte var att undersöka tandhygienisters anledningar till varför anestesi används eller inte används. En enkätstudie skickades till 148 tandhygienister slumpmässigt utvalda av Sveriges Tandhygienistförening. Nittio enkäter (60,8 %) inkluderades i studiens resultat. Anestesi vid depuration användes främst en till två gånger per vecka med ett medelvärde på 38,6 % (±29,8). Ökat fickdjup resulterade i ökad anestesianvändning vid subgingival rengöring (fickdjup 5-6 mm 43,1 VAS, fickdjup 10< mm 82,4 VAS, Visual Analogue Scale). Anestesiförekomsten var lägre vid avlägsning av supragingival tandsten, fyllningsöverskott samt polering med putspasta. Ytanestesi utan efterföljande injektion var den vanligast förekommande anestesitypen, och den minst använda var mandibularinjektioner. De mest förekommande svaren till varför anestesi används var att ge en smärtfri behandling och att anestesi möjliggör ett bättre utfört arbete. Den vanligaste anledningen till varför anestesi inte används var att patienten avböjer. Det kan ifrågasättas om smärtfri behandling sker tillräckligt ofta, då resultatet tyder på att anestesi används för lite i förhållande till hur mycket depuration som utförs.

  • 78.
    Ekelund, Cecilia
    Högskolan Kristianstad, Sektionen för Hälsa och Samhälle.
    Tobaksvanor och kunskaper om tobak och dess effekter i munhålan: En enkätstudie bland sjuksköterske-, tandhygienist- och folkhälsopedagogstudenter vid Högskolan Kristianstad2010Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Bruket av tobak har idag blivit en viktig folkhälsofråga eftersom rökning och snusning har negativa effekter på såväl allmänhälsa som munhälsa. Trots det röker nästan var fjärde svensk kvinna och var femte svensk man. Syftet med den här studien var att kartlägga tobaksvanorna bland förstaårsstudenterna på sjuksköterske-, tandhygienist- och folkhälsopedagogiska programmet samt att undersöka vilka kunskaper studenterna på respektive program har om tobak och dess effekter i munhålan. Studien genomfördes som en enkätundersökning där 121 enkäter delades ut till studenterna på de tre programmen. Resultatet visade att 7% av studenterna var dagligrökare och 17% var feströkare. Störst andel rökare återfanns på tandhygienistprogrammet. Endast 4% av studenterna brukade snus. Lungcancer, KOL och hjärt-kärlsjukdom var de sjukdomstillstånd som flest studenter associerade med tobaksbruk och när det gäller effekterna i munhålan, såg studenterna starka kopplingar till flera av de listade tillstånden. Rökning förknippades främst med dålig andedräkt, missfärgning av tänderna och muncancer medan snusning också förknippades med frätskador på munslemhinnan. Studenterna visade relativt goda kunskaper om tobak och dess effekter på hälsan. Trots detta rökte en stor del av studenterna vilket indikerar att kunskap allena, inte får unga människor att avstå från tobaksbruk.

  • 79.
    Ekenros, Anna
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Svensson, Marie
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Tobaksvanor och uppfattningen om tobakens påverkan i munhålan bland grundlärarstuderande2014Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syfte: Syftet med studien var att kartlägga tobaksvanor och uppfattningen om tobakens påverkan i munhålan bland grundlärarstuderande.

    Material och metod: En tvärsnittsstudie med kvantitativ design genomfördes i form av en enkätundersökning. Enkäten delades ut till 76 grundlärarstudenter där samtliga valde att delta.

    Resultat: Resultatet visade att det var 13 respondenter som rökte och 4 som snusade, varav en var blandbrukare av snus och cigaretter. Debutåldern för rökning var mellan 11-20 år och för snusning mellan 16-20 år. Den övervägande delen av respondenterna hade uppfattningen att tobak har någon form av påverkan i munhålan. En stor del av respondenterna uppfattade att rökning har en mycket stor betydelse för att utveckla tillstånden dålig andedräkt (73,3%) och missfärgning av tänderna (78,9%), medan majoriteten av respondenterna uppfattade att missfärgning av tänderna (82,7%) har en mycket stor betydelse vid användningen av snus.

    Slutsats: Resultatet visar att det var fler tobaksanvändare i denna studie i förhållande till tobaksvändningen i övriga Sverige. Studien visar att den övervägande delen av grundlärarstudenterna uppfattade att rökning och snusning påverkar utveckling av olika tillstånd i munhålan.

  • 80.
    Eklund, Hulda
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Jartelius, Annelie
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Orala problem som förekommer vid ätstörningar2014Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Ätstörningar som anorexia nervosa (AN) och bulimia nervosa (BN) innebär ett folkhälsoproblem som kan orsaka oral ohälsa

    Studiens syfte: Syftet med denna litteraturstudie var att undersöka vilka orala problem som förekommer vid AN och BN.

    Material och metod: Studien genomfördes i form av en litteraturstudie. Material samlades in via sökningar i databasen Web of Science. Resultatet baserades på en sammanställning av sju vetenskapliga artiklar.

    Resultat: Resultatet visade att ett flertal studier har redovisat förekomst av orala förändringar vid diagnoserna AN och BN. Mest förekommande var dentala erosioner och hypertrofi av glandula parotis. Men även förekomst av karies, parodontal sjukdom samt orala slemhinneförändringar och infektioner framgick.

    Slutsats: Slutsatsen med denna studie visar att de mest förekommande orala problemen som uppstår vid AN och BN är dentala erosioner samt hypertrofi av salivkörtlarna, även orala slemhinneförändringar och infektioner förekommer.

  • 81.
    Elias, Dalya
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Nguyen, Wendy
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Kunskap om munhygien och kostvanor hos föräldrar till förskolebarn2015Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syfte: Syftet med denna studie var att undersöka kunskap om munhygien och kostvanor hos föräldrar till förskolebarn.

    Material och metod: Denna kvantitativa empiriska enkätundersökning är baserad på sex bakgrundsfrågor och tretton frågor med fasta och öppna svarsalternativ, angående kunskap om munhygien och kostvanor. Studien utfördes på fyra förskolor i Helsingborg där respondenterna var föräldrar till barn i aktuell förskola. 161 enkäter delades ut. Enkäten besvarades av 91 föräldrar. Det insamlade materialet analyserades med hjälp av Statistical Package for Social Science version 22.0.

    Resultat: Resultatet visade att 86% av föräldrarna kände till att tandborstningen borde introduceras när första tanden bryter fram. Majoriteten av föräldrarna (94%) ansåg att tandborstningen skulle ske 2 gånger/dag, och 69% av föräldrarna angav att tandborstningen ska utföras med vuxenhjälp fram till 10-12-års ålder. Sjuttiofem procent av föräldrarna ansåg att barnen bör äta 3 huvudmål/dag och 92% av föräldrarna svarade att mellanmålsintagen ska ske 2-3 gånger dagligen. Att sockerintaget borde begränsas till 1 gång/vecka svarade 70% av föräldrarna. Tolv procent av föräldrarna ansåg att fluortandkräm inte skulle användas på barn.

    Slutsats: Studien visar att majoriteten av föräldrar som deltog har god kunskap angående kostvanor, men lägre kunskap om munhygien och tandborstning med fluortandkräm.

  • 82.
    Emami, Chiman
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Madjid, Shilan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Sambandet mellan cigarrettrökning och parodontit2011Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syfte: Syftet med studien var att belysa sambandet mellan cigarrettrökning och paro-dontit.Metod: Studien bygger på en allmän litteraturstudie som sammanställer aktuell forsk-ning inom det valda ämnesområdet. Detta studerades genom att granska olika studiers koppling mellan parodontit och cigarrettrökning. Studien baseras på 15 kvantitativa artiklar som söktes via PubMed och Sience Direct.Resultat: Resultatet visade att det fanns ett samband mellan parodontit och cigarrett-rökning. Rökning var den främsta beteendemässiga riskfaktorn för uppkomst av paro-dontit. Rökare uppvisar ett mer ohälsosamt beteende och negativ attityd till allmän hälsa. Kroppens infektionsförsvar försämrades hos rökare. Slutsats: Studien har funnit att det finns ett samband mellan cigarrettrökning och pa-rodontit. Variabler som ålder och kön har ingen påverkan på associationen mellan ci-garettrökning och parodontit. Däremot är det antalet rökta cigarretter per år och anta-let år av konsumtion som har en påverkan för uppkomst av parodontit.

  • 83.
    Emma, Johansson
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Anna, Svensson
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Gymnasieelevers uppfattning om sina tänder, mun och ansikte relaterat till oral hälorelaterad livskvalitet2015Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syfte: Syftet med studien var att undersöka oral hälsorelaterad livskvalitet relaterat till mun, tänder och ansikte hos pojkar och flickor i årskurs 1 på en gymnasieskola.

    Metod: Enkätstudien är en kvantitativ tvärsnittsstudie som utfördes med en svensk version av COHIP-SF 19. I studien ingick 101 elever som alla var födda 1998.

    Resultat: Majoriteten av eleverna svarade att de ”aldrig” eller ”nästan aldrig” haft ont i tänderna/tandvärk. Det sammanlagda medianvärdet för området oral hälsa var 15. Inom området funktionellt välbefinnande fanns en statistisk skillnad mellan könen (p= 0,000) på frågan om de känt att människor haft svårt att förstå vad du säger. Det sammanlagda medianvärdet för området funktionellt välbefinnande var 16. På frågan om de känt att du var attraktiv (snygg) på grund av dina tänder, mun eller ansikte fanns en statistisk skillnad mellan könen (p= 0,022). Det sammanlagda medianvärdet för området social-emotionellt välbefinnande var 35.

    Slutsats: Slutsatsen av studien är att det finns skillnader mellan hur pojkar och flickor uppfattar sin orala hälsorelaterade livskvalitet. Resultatet av studien tyder också på att majoriteten av eleverna har en positiv uppfattning om sina tänder, mun och ansikte relaterat till oral hälsorelaterad livskvalitet.

  • 84.
    Erovic Ademovski, Seida
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL).
    Treatment of intra-oral halitosis2017Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
    Abstract [en]

    Intra-oral  halitosis  (bad  breath)  is reported  to affect  15-83 % of the adult population. Having intra-oral halitosis is a social and psycho-logical handicap, and may cause people in the  person’s social circle to increase the physical distance or to turn their faces in another direction to avoid the unpleasant smell from the exhaled air. Such behaviours may affect the individual’s self-confidence resulting in insecurity in social and intimate relations. The oral health-related quality of life status has also been reported to be lower in individuals with halitosis. Approximately 90% of what is considered as bad breath is the result of the degradation of organic substrates (proteins) by an- aerobic bacteria of the oral cavity. Intra-oral halitosis can be  assessed using both subjective and objective methods to evaluate the subject’s exhaled air. The most common one and the one often referred to as the ”gold standard”, is the organoleptic scoring system (OLS). OLS is a subjective method  evaluating  the  strength  of halitosis in exhaled air using a scale from 0-5. One objective  method to assess the presence of volatile sulphur compounds in exhaled air is to use a sulphide monitor measuring the total sum of the volatile sulphur  compounds  (T-VSC) in exhaled  air.  The three  gases  (hydrogensulphide (H2S), methyl mercaptan (MM) and dimethyl sulphide (DMS)) in exhaled air related to intra-oral halitosis can be assessed separately using a simplified gas chromatograph. Different treatment models such as periodontal treatment, tongue scraping and rinsing with Zn ion containing products have been used to reduce intra-oralhalitosis. The  present  thesis  has  evaluated  the  efficacy of  different treatment models in the treatment of intra-oral  halitosis.

  • 85.
    Erovic Ademovski, Seida
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL).
    Lingström, P
    University of Gothenburg.
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL). Blekinge Institute of Techology, Dublin Dental University Hospital, Dublin.
    The effect of different mouth rinse products on intra-oral halitosis2016Ingår i: International Journal of Dental Hygiene, ISSN 1601-5029, E-ISSN 1601-5037, Vol. 14, nr 2, s. 117-123Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    AIM: To evaluate the effect of different mouth rinses 12 h after rinsing on genuine intra-oral halitosis.

    MATERIALS AND METHODS: Twenty-four adults with halitosis were included in a double-blind, crossover, randomized clinical trial. Halitosis was evaluated 12 h after rinsing with placebo and five mouth rinse products containing zinc acetate and chlorhexidine diacetate; zinc lactate, chlorhexidine and cetylpyridinium chloride; zinc acetate and chlorhexidine diacetate with reduced amounts of mint and menthol; zinc chloride and essential oil; and chlorine dioxide using the organoleptic method and a gas chromatograph. Test periods were separated by 1 week.

    RESULTS: Hydrogen sulphide (H2 S), methyl mercaptan (MM) and the organoleptic scores (OLS) were significantly reduced 12 h following rinsing with all substances compared to placebo (P < 0.05). H2 S was more effectively reduced after rinsing with zinc acetate and chlorhexidine diacetate and zinc acetate and chlorhexidine diacetate with reduced amounts of mint and menthol compared to rinsing with zinc chloride and essential oil (P < 0.05), and significantly lower values of MM were obtained after rinsing with zinc acetate and chlorhexidine diacetate compared to zinc lactate, chlorhexidine and cetylpyridinium chloride (P < 0.05). The percentage effectively treated individuals (H2 S (<112 ppb), MM (<26 ppb) and OLS score <2) varied from 58% percentage (zinc acetate and chlorhexidine diacetate) to 26% (zinc chloride and essential oil).

    CONCLUSION: All treatments resulted in reduction in halitosis 12 h after rinsing compared to placebo. H2 S and MM were most effectively reduced by zinc acetate and chlorhexidine diacetate.

  • 86.
    Erovic Ademovski, Seida
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Lingström, Peter
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Winkel, Edwin
    Academic Centre for Oral Health, Department of Periodontology, University Medical Centre Groningen.
    Tangerman, Albert
    Academic Centre for Oral Health, Department of Periodontology, University Medical Centre Groningen.
    Persson, G. Rutger
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Comparison of different treatment modalities for oral halitosis2012Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 70, nr 3, s. 224-233Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives. To assess the effects on intra-oral halitosis by a mouth rinse containing zinc acetate (0.3%) and chlorhexidine diacetate (0.025%) with and without adjunct tongue scraping. Materials and methods. Twenty-one subjects without a diagnosis of periodontitis were randomized in a cross-over clinical trial. Organoleptic scores (OLS) were assessed to define intra-oral halitosis by total volatile sulfur compound (T-VSC) measurements and by gas chromatography. Results. Twenty-one subjects with a mean age of 45.7 years (SD: ±13.3, range: 21–66). The OLS were significantly lower following active rinse combined with tongue scraping (p < 0.001) at all time points. Immediately after, at 30 min, and at day 14, the T-VSC values were lower in the active rinse sequence than in the negative rinse sequence (p < 0.001, p < 0.001 and p < 0.05, respectively). At 30 min and at day 14, the hydrogen sulfide (H2S) and methyl mercaptan (MM) values were lower in the active rinse sequence compared to the inactive rinse sequence (p < 0.001). The inactive rinse sequence with tongue scraping reduced T-VSC at 30 min (p < 0.001) but not at 14 days. Similar reductions in T-VSC, H2S and MM were found in the active rinse sequence with or without tongue scraping. Conclusion. The use of a tongue scraper did not provide additional benefits to the active mouth rinse, but reduced OLS and tongue coating index.

  • 87.
    Erovic Ademovski, Seida
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL).
    Mårtensson, Carina
    Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL). Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap.
    Persson, Rutger G
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL).
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Oral hälsa och folkhälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL).
    The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral halitosis: a randomized clinical trial2017Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 44, nr 10, s. 1010-1019Artikel i tidskrift (Refereegranskat)
  • 88.
    Erovic Ademovski, Seida
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Hälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet.
    Persson, G. Rutger
    Department of Periodontology, School of Dental Medicine, University of Bern.
    Winkel, Edwin
    Academic Centre for Oral Health, Department of Periodontology, University Medical Centre Groningen.
    Tangerman, Albert
    Department of Gastroenterology and Hepatology, Radboud University Medical Centre, Nijmegen.
    Lingström, Peter
    Department of Cariology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg.
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Hälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet.
    The short-term treatment effects on the microbiota at the dorsum of the tongue in intra-oral halitosis patients: a randomized clinical trial2013Ingår i: Clinical Oral Investigations, ISSN 1432-6981, E-ISSN 1436-3771, Vol. 17, nr 2, s. 463-473Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Objectives This study aims to assess the effects of rinsing with zinc- and chlorhexidine-containing mouth rinse with or without adjunct tongue scraping on volatile sulfur compounds (VSCs) in breath air, and the microbiota at the dorsum of the tongue. Material and methods A randomized single-masked controlled clinical trial with a cross-over study design over 14 days including 21 subjects was performed. Bacterial samples from the dorsum of the tongue were assayed by checkerboard DNA–DNA hybridization. Results No halitosis (identified by VSC assessments) at day 14 was identified in 12/21 subjects with active rinse alone, in 10/21with adjunct use of tongue scraper, in 1/21 for negative control rinse alone, and in 3/21 in the control and tongue scraping sequence. At day 14, significantly lower counts were identified only in the active rinse sequence ( p &lt; 0.001) for 15/78 species including , Fusobacterium sp., Porphyromonas gingivalis , Pseudomonas aeruginosa , Staphylococcus aureus , and Tannerella forsythia . A decrease in bacteria from baseline to day 14 was found in successfully treated subjects for 9/74 species including: P. gingivalis , Prevotella melaninogenica , S. aureus , and Treponema denticola . Baseline VSC scores were correlated with several bacterial species. The use of a tongue scraper combined with active rinse did not change the levels of VSC compared to rinsing alone. Conclusions VSC scores were not associated with bacterial counts in samples taken from the dorsum of the tongue. The active rinse alone containing zinc and chlorhexidine had effects on intra-oral halitosis and reduced bacterial counts of species associated with malodor. Tongue scraping provided no beneficial effects on the microbiota studied. Clinical relevance Periodontally healthy subjects with intra-oral halitosis benefit from daily rinsing with zinc- and chlorhexidine-containing mouth rinse.

  • 89.
    Erovic, Seida
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Lingström, P.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Winkel, E.
    Tangerman, A.
    Persson, G. Rutger
    Bern, Switzerland.
    The effect on bad breath using a zinc-lacete - chlorhexidine containing mouth rinse2009Ingår i: Europerio 6: Stockholm, Sweden, 4-6 June 2009 / [ed] Tonetti, Maurizio, Renvert, Stefan, 2009, s. 37-Konferensbidrag (Refereegranskat)
    Abstract [en]

    Background: Around 30% of the adult population has problems with Halitosis. Halitosis is caused by volatile sulfur compounds (VSC) by bacteria. The aim of this study was to evaluate the short term effect on halitosis using a zinc-lacete-chlorhexidine containing mouth rinse (SB12). Materials and methods: Twenty-five adults with halitosis were included in a clinical randomized double blind cross over study. Four test periods, each 2 weeks long separated by washout periods of 1 week was used to evaluate 4 treatments: A) SB12, B) placebo C) SB12 + tongue scraper, and D) placebo + tongue scraper. Registration of VSC using a Halimeter was done at Day 1 before rinsing, immediately after rinsing, after 30 minutes and at Day 14. Results: A reduction on VSC 30 min following treatment compared to baseline was found for substance A, C, D (P < 0.000). A reduction at Day 14 was only found for substance A (P < 0.004). Comparing treatments, significant differences was found at all time points between A and B (P < 0.01, P < 0.003, P < 0.042 respectively) and between C and B immediately after rinsing and 30 min after rinsing (P < 0.008, P < 0.003). There was non significant difference between treatment A and C or between treatments B and D. Conclusion: Rinsing with a zinc-lacete - chlorhexidine containing mouth rinse (SB12) demonstrated short term reductions of VSC. Tongue scraper alone had a limited effect on oral halitosis. The addition of tongue cleaning using a tongue scraper did not improve the results obtained by rinsing alone.

  • 90.
    Fagrell, Tobias G.
    et al.
    Specialist Clinic of Pedodontics, Sahlgrenska University Hospital Mölndal.
    Dietz, Wolfram
    University of Jena.
    Lingström, Peter
    Högskolan Kristianstad, Institutionen för hälsovetenskaper.
    Steiniger, Frank
    University of Jena.
    Norén, Jörgen G.
    University of Gothenburg.
    Effect of ozone treatment on different cariogenic microorganisms in vitro2008Ingår i: Swedish Dental Journal, ISSN 0347-9994, Vol. 32, nr 3, s. 139-147Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Ozone treatment has been presented and discussed in the literature, as one of the "new" ways to treat dental caries. The aim of this paper was to study the in vitro effect of ozone on some common oral microorganisms related to dental caries using scanning electron microscopy (SEM). The effect of ozone was tested on three different strains of mutans streptococci and one Lactobacillus strain. After exposure of bacteria to ozone treatment for 0 to 60 sec, cultivation on different chair side strips and agar plates took place. Preparation and performance of scanning electron analyses in a field emission scanning electron microscope at 10 kV was then carried out. It was found that gaseous ozone treatment for 20 seconds or more was effective to kill the different microorganisms in vitro. Treatment of 20, 40 and 60 seconds of ozone prevented the bacteria to grow on the different media. Treatment times shorter than 20 seconds resulted in varying results with a limited effect on bacterial growth for treatments of 5-10 sec, respectively. The difference between ozone-treated and untreated specimens was macroscopically readily discernable. None of the strains treated with ozone for 60 seconds showed any bacterial growth. Only samples with untreated bacteria could be found in the SEM analyses in form of large and high colonies. This study presents a clear result of the bactericide effect of ozon (in vitro) on four different strains of bacteria associated with dental caries.

  • 91.
    Fagrell, Tobias G.
    et al.
    Pediatric Dentistry Special Dental Service, Sahlgrenska University Hospital, Mölndal.
    Lingström, Peter
    Högskolan Kristianstad, Institutionen för hälsovetenskaper.
    Olsson, Stina
    Department of Oral Pathology, Institute of Odontology, Sahlgrenska Academy, Göteborg University.
    Steiniger, Frank
    Centre of Electron Microscopy, Friedrich-Schiller-University, Jena.
    Norén, Jörgen G
    Department of Pedodontics, Institute of Odontology, Sahlgrenska Academy, Göteborg University.
    Bacterial invasion of dentinal tubules beneath apparently intact but hypomineralized enamel in molar teeth with molar incisor hypomineralization2008Ingår i: International Journal of Paediatric Dentistry, ISSN 0960-7439, E-ISSN 1365-263X, Vol. 18, nr 5, s. 333-340Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: The most common problems for a patient with molar incisor hypomineralization (MIH) are the collapse of enamel and cavitations, loss of fillings, and secondary caries, but most of all, severe hypersensitivity. OBJECTIVE: The aim of this paper was therefore to histologically study possible bacterial invasion of dentinal tubules beneath apparently intact, but hypomineralized enamel in permanent molars with MIH. MATERIAL AND METHODS: Five extracted permanent first molars diagnosed with MIH were fixated, demineralized, and sagittally serially sectioned in a bucco-lingual direction in a microtome with a thickness of 4-5 microm. Sections were stained with a modified Brown and Benn staining for bacteria, unstained sections were analysed in field emission SEM. RESULTS: Stained sections from the cuspal areas, below the hypomineralized enamel, the staining indicated the presence of bacteria in the dentinal tubules. The HTX staining showed that the pulp in sections without any findings was normal and free from bacteria or infiltrates from inflammatory cells. In sections where bacteria were found in the cuspal areas or deeper in the dentin, a zone of reparative dentin was found, and in sections from one tooth, the coronal pulp showed an inflammatory reaction with inflammatory cells. In sections adjacent to those without any bacterial staining, the SEM analyses revealed empty dentinal tubules without any odontoblast processes or signs of bacteria. When odontoblast processes were found, the dentinal tubules were filled with bacteria located on the surface of the odontoblast processes. In some areas, a large number of tubules were found with bacteria. No bacteria were found close to the pulp. The odontoblast processes appeared larger in areas where bacteria were found. CONCLUSIONS: The presence of bacteria in the dentinal tubules and inflammatory reactions in the pulp indicate that oral bacteria may penetrate through the hypomineralized enamel into the dentin, thus possibly contribute to hypersensitivity of teeth with MIH.

  • 92.
    Fardal, Øystein
    et al.
    Private practice, Egersund.
    Fardal, Patrick
    Dublin Dental University Hospital, Dublin.
    Persson, G. Rutger
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Hälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet.
    Periodontal and general health in long-term periodontal maintenance patients treated in a Norwegian private practice: a descriptive report from a compliant and partially compliant survivor population2013Ingår i: Journal of Periodontology, ISSN 0022-3492, E-ISSN 1943-3670, Vol. 84, nr 10, s. 1374-1381Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background There is weak evidence to support the benefit of periodontal maintenance therapy in preventing tooth loss. In addition, the effects of long-term periodontal treatment on general health are unclear.

    Materials/Methods Compliant and partially compliant patients (15-25 years follow-up) in private practice were observed for oral and systemic health changes.

    Results 219 compliant patients (128 females, 91 males) were observed for 19.1 years (range 15-25, SD ± 2.8). Age at reassessment was 64.6 years (range 39-84 SD ±9.0). 145 patients were stable (0-3 teeth lost), 54 were downhill (4-6 teeth lost) and 21 patients extreme downhill (>6 teeth lost). 16 patients developed hypertension, 13 developed diabetes II, and 15 suffered myocardial infarcts (MI). A minority developed other systemic diseases. Risk factors for MI included overweight (OR 9.04,95% CI:2.9-27.8, p=0.000), family history with cardiovascular disease (OR 3.10, 95 % CI:1.07-8.94, p=0.029), diabetes I at baseline (p=0.02) and developing diabetes II (O.R. 7.9, 95 % CI: 2.09-29.65, p=0.000). 25 partially compliant patients (8 females, 17 males) were observed for 19 years. This group had a higher proportion of downhill and extreme downhill cases and MI.

    Conclusion Patients who left the maintenance program in a periodontal specialist practice in Norway had a higher rate of tooth loss than compliant patients. Compliant maintenance patients in specialist practice in Norway have a similar risk of developing diabetes type II as the general population. A rate of 0.0037 myocardial infarcts per patient per year was recorded for this group. Due to the lack of external data, it is difficult to assess how this compares with untreated periodontal patients.

  • 93.
    Fast, My
    et al.
    Högskolan Kristianstad, Fakulteten för hälsovetenskap.
    Dedović, Lejla
    Högskolan Kristianstad, Fakulteten för hälsovetenskap.
    Sjuksköterskestudenters kunskaper om munygien och munhygienhjälpmedel2019Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    Syftet med denna kvantitativa studie var att undersöka kunskaper om munhygien och munhygienhjälpmedel hos sjuksköterskestudenter i termin fyra och fem vid högskolan i Kristianstad. Metoden som har använts är en kvantitativ empirisk studie med enkät som datainsamling. Enkäten omfattade frågor angående sjuksköterskestudenternas kunskaper om munhygien och munhygienhjälpmedel. Enkäten hade fasta svarsalternativ.

    I studien inkluderades 113 enkäter. Av sjuksköterskorna angav 97,3% att den främsta orsaken till tandborstning är att avlägsna bakterier. Gällande rutiner kring tandborstning angav majoriteten att tänderna bör borstas två gånger per dag (96,4%), i två minuter (69%). Respondenterna (51,4%) angav att tänderna bör borstas mjukare vid blödande tandkött. Samtliga studenter (100%) angav att approximal rengöring utförs för att avlägsna bakterier mellan tänderna och 73,4% ansåg att tandtråd bör användas vid trånga approximalrum. Av respondenterna ansåg 90,7% att tungskrapa bör användas för att avlägsna bakterier på tungryggen. Vid frågan om fluorets främsta nytta svarade 92,7% att fluor motverkar hål i tänderna. Slutsatsen är att flertalet av sjuksköterskestudenterna i termin fyra och fem vid högskolan i Kristianstad besitter relativt goda kunskaper om munhygien och munhygienhjälpmedel. För att ytterligare öka kunskaperna inom munhygien och munhygienhjälpmedel krävs mer utbildning inom området oral hälsa.

  • 94.
    Figuero, Elena
    et al.
    University Complutense, Madrid.
    Lindahl, Christel
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Hälsovetenskap III. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet.
    Marín, María José
    University Complutense, Madrid.
    Renvert, Stefan
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Hälsovetenskap III. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet.
    Herrera, David
    University Complutense, Madrid.
    Ohlsson, Ola
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Hälsovetenskap I. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet.
    Wetterling, Thomas
    Central Hospital Kristianstad.
    Sanz, Mariano
    University Complutense, Madrid.
    Quantification of periodontal pathogens in vascular, blood and subgingival samples from patients with peripheral arterial disease or abdominal aortic aneurysms2014Ingår i: Journal of Periodontology, ISSN 0022-3492, E-ISSN 1943-3670, Vol. 85, nr 9, s. 1182-1193Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Background: The aim of this investigation was to quantify periodontal pathogens (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Campylobacter rectus and Tannerella forsythia) in vascular, blood and subgingival samples. As secondary objective, two molecular bacterial identification methods [nested-polimerase chain reaction (PCR) and quantitative PCR (qPCR)] were compared.

    Methods: Seventy consecutive patients provided a vascular lesion, a blood sample, and 36 subgingival samples. Bacterial deoxyribonucleic acid (DNA) was extracted and qPCR was used to determine the prevalence and amounts of the target pathogens in each sample. Nested-PCR was only performed in the samples from vascular lesions. Periodontal examination was performed in 42 patients. U-Mann-Whitney or Chi-squared tests were used to compare microbiological results according to periodontal diagnosis.

    Results: All targeted periodontal pathogens (A. actinomycetemcomitans, P. gingivalis, T. forsythia or C. rectus) were detected in subgingival samples with a prevalence rate of 72.2%, 47.2%, 74.3% and 82.9%, respectively. In 7.1% and 11.4% of vascular and blood samples, bacterial DNA was detected. One patient was positive for A. actinomycetemcomitans in the three types of samples. No differences were found in the levels of targeted bacteria when comparing periodontitis and non-periodontitis patients. Prevalence rates obtained with nested PCR were significantly higher than those obtained by qPCR.

    Conclusions: The presence of of A. actinomycetemcomitans was demonstrated in vascular, blood and subgingival samples in one out of 36 patients. These results, although with a very low frequency, may support the hypothesis of a translocation of periodontal pathogens from subgingival microbiota to the blood stream and then to atheromatous plaques in carotid or other peripheral arteries. Nested-PCR is not an adequate method for identifying DNA of periodontal pathogens in low quantities, due to the high number of false negative results.

  • 95.
    Fischer, Carolin C
    et al.
    University of Bern, Bern, Switzerland.
    Persson, Rigmor E
    University of Bern, Bern, Switzerland & University of Washington.
    Persson, G. Rutger
    University of Bern, Bern, Switzerland & University of Washington, Seattle, WA.
    Influence of the menstrual cycle on the oral microbial flora in women: a case-control study including men as control subjects.2008Ingår i: Journal of Periodontology, ISSN 0022-3492, E-ISSN 1943-3670, Vol. 79, nr 10, s. 1966-1973Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    UNLABELLED: Changes in the levels of female sex hormones during the menstrual cycle may cause cyclic differences in subgingival bacterial colonization patterns. The purpose of the present study was to test the hypothesis that hormonal changes in the menstrual cycle cause changes in the oral microbiota.

    METHODS: Bacterial plaque samples were collected in 20 systemically and periodontally healthy women using no hormonal contraceptives (test group) over a period of 6 weeks. Twenty age-matched systemically and periodontally healthy men were assigned to the control group. Samples were processed by checkerboard DNA-DNA hybridization assay, and 74 species were analyzed.

    RESULTS: No cyclic pattern of bacterial colonization was identified for any of the 74 species studied in women not using hormonal contraceptives. Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans) (Y4) was common at the beginning of menstruation (mean: 32%) and increased during the following 2 weeks (36%) in women (P <0.05). No cyclic differences in bacterial presence were found among the men (P values varied between 0.14 and 0.98). Men presented with significantly higher bacterial counts for 40 of 74 species (P <0.001), including Staphylococcus aureus and Pseudomonas aeruginosa but not Porphyromonas gingivalis (P = 0.15) or Tannerella forsythia (previously T. forsythensis) (P = 0.42).

    CONCLUSIONS: During a menstruation period, cyclic variation in the subgingival microbiota of periodontally healthy women of child-bearing age who were not using oral hormonal contraceptives could not be confirmed. Male control subjects presented with higher levels of many species but also without a cyclic pattern.

  • 96.
    Fritschi, B Zinsli
    et al.
    University of Berne, School of Dental Medicine, Freiburgstrasse 7, CH-3010 Berne, Switzerland.
    Albert-Kiszely, A
    University of Berne, School of Dental Medicine, Freiburgstrasse 7, CH-3010 Berne, Switzerland.
    Persson, G. Rutger
    University of Bern, Bern, Switzerland & University of Washington, Seattle, WA, USA.
    Staphylococcus aureus and other bacteria in untreated periodontitis.2008Ingår i: Journal of Dental Research, ISSN 0022-0345, E-ISSN 1544-0591, Vol. 87, nr 6, s. 589-593Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Whether the subgingival microbiota differ between individuals with chronic and those with aggressive periodontitis, and whether smoking influences bacterial composition, is controversial. We hypothesized that the subgingival microbiota do not differ between sites in individuals with chronic or aggressive periodontitis, or by smoking status. Bacterial counts and proportional distributions were assessed in 84 individuals with chronic periodontitis and 22 with aggressive periodontitis. No differences in probing pocket depth by periodontal status were found (mean, 0.11 mm; 95% CI, 0.6 to 0.8, p = 0.74). Including Staphylococcus aureus, Parvimonas micra, and Prevotella intermedia, 7/40 species were found at higher levels in those with aggressive periodontitis (p < 0.001). Smokers had higher counts of Tannerella forsythia (p < 0.01). The prevalence of S. aureus in non-smokers with aggressive periodontitis was 60.5%. The null hypothesis was rejected, in that P. intermedia, S. aureus, and S. mutans were robust in diagnosing sites in individuals with aggressive periodontitis. S. aureus, S. sanguinis, and T. forsythia differentiated smoking status.

  • 97.
    Fürst, Mirjam M
    et al.
    Department of Periodontology and Fixed Prosthodontics, School of Dental Medicine, University of Berne, Berne, Switzerland.
    Salvi, Giovanni E
    Department of Periodontology and Fixed Prosthodontics, School of Dental Medicine, University of Berne, Berne, Switzerland.
    Lang, Niklaus P
    Department of Periodontology and Fixed Prosthodontics, School of Dental Medicine, University of Berne, Berne, Switzerland.
    Persson, G. Rutger
    Department of Periodontology and Fixed Prosthodontics, School of Dental Medicine, University of Berne, Berne, Switzerland.
    Bacterial colonization immediately after installation on oral titanium implants.2007Ingår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 18, nr 4, s. 501-8Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    BACKGROUND: Information on bacterial colonization immediately after dental implant insertion is limited.

    AIMS: (1) To assess the early colonization on titanium implants immediately after placement and throughout the first 12 post-surgical weeks, (2) to compare the microbiota at interproximal subgingival implant and adjacent tooth sites.

    MATERIAL AND METHODS: Subgingival plaque samples from implant and neighbouring teeth were studied by checkerboard DNA-DNA hybridization before surgery, 30 min after implant placement, and 1, 2, 4, 8, and 12 weeks after surgery.

    RESULTS: Comparing bacterial loads at implant sites between 30 min after placement with 1-week data showed that only the levels of Veillonella parvula (P<0.05) differed with higher loads at week 1 post-surgically. Week 12 data demonstrated significantly higher bacterial loads for 15/40 species at tooth sites compared with pre-surgery (P-values varying between 0.05 and 0.01). Between the period immediately after surgery and 12 weeks at implant sites, 29/40 species was more commonly found at 12 weeks. Included among these bacteria at implant sites were Porphyromonas gingivalis (P<0.05), Tannerella forsythia, (P<0.01), and Treponema denticola (P<0.001). Immediately post-surgery 5.9% of implants, and 26.2% of teeth, and at week 12, 15% of implants, and 39.1% of teeth harbored Staphylococcus aureus. Comparing tooth and implant sites, significantly higher bacterial loads were found at tooth sites for 27/40 species after 30 min following implant placement. This difference increased to 35/40 species at 12 weeks post-surgically.

    CONCLUSIONS: Bacterial colonization occurred within 30 min after implant placement. Early colonization patterns differed between implant and tooth surfaces.

  • 98.
    Gerber, Jeanne
    et al.
    Department of Periodontology and Fixed Prosthodontics, University of Berne, Berne, Switzerland.
    Wenaweser, Doris
    Department of Periodontology and Fixed Prosthodontics, University of Berne, Berne, Switzerland.
    Heitz-Mayfield, Lisa
    Department of Periodontology and Fixed Prosthodontics, University of Berne, Berne, Switzerland.
    Lang, Niklaus P
    Department of Periodontology and Fixed Prosthodontics, University of Berne, Berne, Switzerland.
    Persson, G. Rutger
    Department of Periodontology and Fixed Prosthodontics, University of Berne, Berne, Switzerland & Departments of Periodontics and Oral Medicine, University of Washington, Seattle, WA, USA.
    Comparison of bacterial plaque samples from titanium implant and tooth surfaces by different methods.2006Ingår i: Clinical Oral Implants Research, ISSN 0905-7161, E-ISSN 1600-0501, Vol. 17, nr 1, s. 1-7Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Studies have shown similarities in the microflora between titanium implants or tooth sites when samples are taken by gingival crevicular fluid (GCF) sampling methods. The purpose of the present study was to study the microflora from curette and GCF samples using the checkerboard DNA-DNA hybridization method to assess the microflora of patients who had at least one oral osseo-integrated implant and who were otherwise dentate. Plaque samples were taken from tooth/implant surfaces and from sulcular gingival surfaces with curettes, and from gingival fluid using filter papers. A total of 28 subjects (11 females) were enrolled in the study. The mean age of the subjects was 64.1 years (SD+/-4.7). On average, the implants studied had been in function for 3.7 years (SD+/-2.9). The proportion of Streptococcus oralis (P<0.02) and Fusobacterium periodonticum (P<0.02) was significantly higher at tooth sites (curette samples). The GCF samples yielded higher proportions for 28/40 species studies (P-values varying between 0.05 and 0.001). The proportions of Tannerella forsythia (T. forsythensis), and Treponema denticola were both higher in GCF samples (P<0.02 and P<0.05, respectively) than in curette samples (implant sites). The microbial composition in gingival fluid from samples taken at implant sites differed partly from that of curette samples taken from implant surfaces or from sulcular soft tissues, providing higher counts for most bacteria studied at implant surfaces, but with the exception of Porphyromonas gingivalis. A combination of GCF and curette sampling methods might be the most representative sample method.

  • 99.
    Ghaffari, Dominique
    et al.
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Thach, Katarina
    Högskolan Kristianstad, Sektionen för hälsa och samhälle.
    Samband mellan kostrelaterad övervikt eller fetma och karies hos barn2014Självständigt arbete på grundnivå (kandidatexamen), 10 poäng / 15 hpStudentuppsats (Examensarbete)
    Abstract [sv]

    En av de ledande dödsorsakerna i världen beror på övervikt och fetma, därför är det viktigt att barn utvecklar bra kostvanor under tidig ålder. Syftet med denna litteraturstudie var att undersöka sambandet mellan kostrelaterad övervikt/fetma och karies hos barn. Artiklarna söktes i den medicinska databasen PubMed. Åldersbegränsning gjordes på barn mellan 0-18 år på grund av att studien är fokuserad på barn. Resultatet baseras på 10 vetenskapliga artiklar. Alla utom två studier har kommit fram till att barn med övervikt eller fetma (BMI >25) hade högre prevalens av karies jämfört med normalviktiga eller underviktiga barn. Flera av studierna redovisade också att de överviktiga barnen hade högre konsumtion av snabbmat, sockerrik dryck och mat som innehåller jäsbara kolhydrater. I de studier där fettrik föda intogs fanns inget samband med karies. I en av de studier där de inte fann något samband mellan övervikt (BMI >25) och karies fanns istället samband mellan undervikt (BMI <18) och karies. Studiens slutsats är att kosten kan innebära ett möjligt samband mellan övervikt/fetma och karies. Det behövs dock ytterligare forskning genom framförallt longitudinella studier inom området för att fastställa sambandet.

  • 100.
    Gonda, Tomoya
    et al.
    Osaka University.
    Macentee, Michael I.
    University of British Columbia.
    Kiyak, H. Asuman
    University of Washington.
    Persson, G. Rutger
    Högskolan Kristianstad, Sektionen för hälsa och samhälle, Avdelningen för Hälsovetenskap. Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet.
    Persson, Rigmor E.
    University of Washington.
    Wyatt, Christopher
    University of British Columbia.
    Predictors of multiple tooth loss among socioculturally diverse elderly subjects2013Ingår i: International Journal of Prosthodontics, ISSN 0893-2174, E-ISSN 1139-9791, Vol. 26, nr 2, s. 127-134Artikel i tidskrift (Refereegranskat)
    Abstract [en]

    Purpose: This study identifies clinical factors that predict multiple tooth loss in a socioculturally diverse population of older adults.

    Materials and Methods: A total of 193 participants from English-, Chinese-, or Punjabi-speaking communities in Vancouver, British Columbia, with low incomes and irregular use of dental services were followed for 5 years as part of a clinical trial of a 0.12% chlorhexidine mouthrinse. The participants were interviewed and examined clinically, including panoramic radiographs, at baseline and annually for 5 years. Binary logistic regression was used to test the hypothesis that there was no difference between incidence of multiple (≥ 3) tooth loss in older people with various biologic, behavioral, prosthodontic, and cultural variables over 5 years.

    Results: Multiple tooth loss, which was distributed similarly among the groups in the trial, occurred in 39 (20%) participants over 5 years. The use of removable prostheses was the best predictor of loss, followed by the number of carious surfaces and number of sites with gingival attachment loss > 6 mm. The pattern of prediction was consistent across the three linguocultural groups.

    Conclusion: The use of removable dentures was the dominant predictor of multiple tooth loss in the three communities, but that tooth loss was not significantly associated with the cultural heritage of the participants.

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