Nurse led clinics have successfully been taking care of large groups of patients suffering from chronic diseases such as diabetes, asthma and heart failure (Eklund, 2009). In Sweden today, four out of ten women and five out of ten men, suffers from overweight or obesity (SCB, 2012). Obesity is a global public health problem leading to a host of serious consequences, physical, psychological and social, and has become an ever greater challenge for our society to find solutions and effective treatments for (WHO, 2013). Recently nurse led obesity clinics has been established. The purpose of this paper is to describe nursing interventions in nurse led obesity clinic. The thesis is a literature study based on both qualitative and quantitative items. The results obtained suggest that nurse led interventions in overweight clinic is based on a holistic approach where the nurse's role is to support the patient and in partnership with him or her develop a person-centered care that encompasses both body and soul.