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No altered dorsal anterior cingulate activation in bipolar II disorder patients during a Go/No-go task: an fMRI study.
Institute of Psychiatry, University of Oslo & Department of Psychiatry, Ulleval University Hospital, Oslo.ORCID iD: 0000-0001-6841-1808
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2009 (English)In: Bipolar Disorders, ISSN 1398-5647, E-ISSN 1399-5618, Vol. 11, no 3, 270-279 p.Article in journal (Refereed) Published
Abstract [en]

OBJECTIVES: It has been reported that one of the core features in patients with bipolar disorder II (BD II) is increased impulsivity. The aim of this study was to investigate whether patients with BD II showed decreased activation in the dorsal anterior cingulate cortex (dACC) as compared to healthy controls when performing a task sensitive to impulsivity.

METHODS: Twenty-seven BD II patients and 28 healthy controls performed a Go/No-go task during a functional magnetic resonance imaging (fMRI) session. Eleven of the patients were unmedicated, and possible group differences between medicated and unmedicated patients were also assessed. Results: The groups did not differ in behavioral performance on the Go/No-go task. Both BD II subjects and healthy controls demonstrated dACC activity during the task, and analyses revealed no statistically significant group differences. Medicated and unmedicated patients also did not differ in the degree of fMRI activation.

CONCLUSIONS: These findings do not support the hypothesis of abnormal dACC activity during a Go/No-go task in BD II patients.

Place, publisher, year, edition, pages
2009. Vol. 11, no 3, 270-279 p.
National Category
Neurosciences Psychiatry
Identifiers
URN: urn:nbn:se:hkr:diva-12344DOI: 10.1111/j.1399-5618.2009.00680.xISI: 000265185000003PubMedID: 19419384OAI: oai:DiVA.org:hkr-12344DiVA: diva2:732634
Available from: 2014-07-04 Created: 2014-07-04 Last updated: 2017-12-05Bibliographically approved

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Jensen, Jimmy

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CiteExportLink to record
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  • apa
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  • de-DE
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  • Other locale
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Output format
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