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Chlorhexidine and preservation of sound tooth structure in older adults: A placebo-controlled trial
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2007 (English)In: Caries Research, ISSN 0008-6568, E-ISSN 1421-976X, Vol. 41, no 2, 93-101 p.Article in journal (Refereed) Published
Abstract [en]

The Trial to Enhance Elderly Teeth Health (TEETH) was designed to test the impact of regular rinsing with a 0.12% chlorhexidine (CHX) solution on tooth loss, and the causes of tooth loss (caries, periodontal disease and trauma) were also investigated. This paper reports on the effectiveness of a 0.12% CHX solution for controlling caries using a tooth surface (coronal and root) survival analysis. A total of 1,101 low income elders in Seattle (United States) and Vancouver (Canada), aged 60-75 years, were recruited for a double-blind clinical trial and assigned to either a CHX (n = 550) or a placebo (n = 551) mouth rinse. Subjects alternated between daily rinsing for 1 month, followed by weekly rinsing for 5 months. All sound coronal and root surfaces at baseline were followed annually for up to 5 years. At each follow-up examination, those tooth surfaces with caries, restored, or extracted were scored as 'carious'. The hazard ratio associated with CHX for a sound surface to become filled, decayed, or extracted was 0.87 for coronal surfaces (95% confidence interval: 0.71-1.14, p = 0.20) and 0.91 for root surfaces (95% confidence interval: 0.73-1.14, p = 0.41). These findings suggest that regular rinsing with CHX does not have a substantial effect on the preservation of sound tooth structure in older adults.

Place, publisher, year, edition, pages
2007. Vol. 41, no 2, 93-101 p.
National Category
Dentistry
Identifiers
URN: urn:nbn:se:hkr:diva-12271DOI: 10.1159/000098041ISI: 000244107900002PubMedID: 17284909OAI: oai:DiVA.org:hkr-12271DiVA: diva2:729906
Available from: 2014-06-26 Created: 2014-06-26 Last updated: 2014-09-18Bibliographically approved

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CiteExportLink to record
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Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf