hkr.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Individual variation in influenza A virus infection histories and long-term immune responses in mallards
Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), Linnaeus University, Kalmar.
Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), Linnaeus University, Kalmar.
Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), Linnaeus University, Kalmar.
Centre for Ecology and Evolution in Microbial Model Systems (EEMiS), Linnaeus University, Kalmar.
Show others and affiliations
2013 (English)In: PLoS ONE, ISSN 1932-6203, Vol. 8, no 4, e61201- p.Article in journal (Refereed) Published
Abstract [en]

Wild dabbling ducks (genus Anas) are the main reservoir for influenza A virus (IAV) in the Northern Hemisphere. Current understanding of disease dynamics and epidemiology in this virus-host system has primarily been based on populationlevel ,surveillance studies and infection experiments conducted in laboratory settings. Using a combined experimentalnatural approach with wild-strain captive mallards (Anas platyrhynchos), we monitored individual IAV infection histories and immunological responses of 10 birds over the course of 15 months. This is the first detailed study to track natural IAV infection histories over several seasons amongst the same individuals growing from juvenile to adults. The general trends in the infection histories of the monitored birds reflected seasonal variation in prevalence at the population level. However, within the study group there were significant differences between individuals in infection frequency as well as in short and long term anti-IAV antibody response. Further observations included individual variation in the number of infecting virus subtypes, and a strong tendency for long-lasting hemagglutinin-related homosubtypic immunity. Specifically, all infections in the second autumn, except one, were of different subtypes compared to the first autumn. The variation among birds concerning these epidemiologically important traits illustrates the necessity for IAV studies to move from the level of populations to examine individuals in order to further our understanding of IAV disease and epidemiology.

Place, publisher, year, edition, pages
2013. Vol. 8, no 4, e61201- p.
National Category
Microbiology Ecology
Identifiers
URN: urn:nbn:se:hkr:diva-10083DOI: 10.1371/journal.pone.0061201ISI: 000318008400029PubMedID: 23637797OAI: oai:DiVA.org:hkr-10083DiVA: diva2:600321
Funder
Swedish Research Council, 2010-3067, 2010-5399, 2011-3568Formas, 2009-1220
Available from: 2013-01-24 Created: 2013-01-24 Last updated: 2014-06-05Bibliographically approved

Open Access in DiVA

fulltext(415 kB)95 downloads
File information
File name FULLTEXT01.pdfFile size 415 kBChecksum SHA-512
cc8ac6241c7e856d6ce12c64f4acb0352c2f6e0bedc84592fe960afee807e107e62ed5bc80d66fa45ac6c433e1d49d323588b6453b781ee3a61e7f19b52fdf3d
Type fulltextMimetype application/pdf

Other links

Publisher's full textPubMed

Search in DiVA

By author/editor
Gunnarsson, GunnarElmberg, Johan
By organisation
Avdelningen för NaturvetenskapForskningsmiljön Man and Biosphere Health (MABH)
In the same journal
PLoS ONE
MicrobiologyEcology

Search outside of DiVA

GoogleGoogle Scholar
Total: 95 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

Altmetric score

Total: 72 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf