With good knowledge about the disease and the treatment, the fear and worry of children and parents can be reduced. Children may be helped by painting to express their experiences. In order to have a good care, the care-personnel need to see and understand what the children need. It is important to live an as regular life as possible during the disease and its treatment. The aim of this study was to elucidate how children experience chemotherapy in conection with their cancer disease. The method that was chosen was an systematic literature review. The result was based on five qualitative articles, which could be divided into four categories: to feel afraid and worried, to feel limited, to feel different and to feel sick. Discussion: There is risk that important information that the children want to tell will go lost when parents and care-personnels communicate children’s experiences to a third part. There is reaserch telling that children may need an adult to help express their experiences.