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Ethanol reduces asymmetry of visual rCBF responses
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1994 (English)In: Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, E-ISSN 1559-7016, Vol. 14, no 6, p. 963-973Article in journal (Refereed) Published
Abstract [en]

Visual regional CBF (rCBF) responses were measured in 10 healthy male subjects before and after an ethanol dose of 1 g/kg body weight. This dose induces well-established cerebral vasodilatation. However, significant bilateral occipital increases were found in both conditions. Apparently, the coupling between neuronal activity and rCBF is preserved following ethanol. The occipital and posterior parietal flow increases were, however, larger on the right than the left side in the sober state. During inebriation the asymmetry disappeared, possibly representing a more undifferentiated processing of visual information. We propose that ethanol causes a reduced inhibition of the left posterior cortex and a reduction of right-hemisphere information processing.

Place, publisher, year, edition, pages
1994. Vol. 14, no 6, p. 963-973
Keywords [en]
Adult, Analysis of Variance, Cerebrovascular Circulation/*drug effects, Ethanol/blood/*pharmacology, Human, Laterality, Male, Occipital Lobe/blood supply, Osmolar Concentration, Photic Stimulation, Reference Values, Regional Blood Flow/drug effects, Support, Non-U.S. Gov't
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Psychology (excluding Applied Psychology) Social Sciences
Identifiers
URN: urn:nbn:se:hkr:diva-686DOI: 10.1038/jcbfm.1994.129ISI: A1994PM72100011PubMedID: 7929660OAI: oai:DiVA.org:hkr-686DiVA, id: diva2:209163
Available from: 2009-03-24 Created: 2009-03-20 Last updated: 2017-12-13Bibliographically approved

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Stenberg, Georg

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