Measuring inflammatory markers in saliva in polyphenols research
2016 (English)In: XXIX INTERNATIONAL HORTICULTURAL CONGRESS ON HORTICULTURE: SUSTAINING LIVES, LIVELIHOODS AND LANDSCAPES (IHC2014): II INTERNATIONAL BERRY FRUIT SYMPOSIUM: INTERACTIONS! LOCAL AND GLOBAL BERRY RESEARCH AND INNOVATION / [ed] Finn, CE & Mezzetti, B, 2016, 201-206 p.Conference paper (Refereed)
There is currently an interest in the possible anti-inflammatory effects of intake of fruits and berries. The aim of this study was to determine whether the twice daily administration of a berry beverage rich in polyphenols had effects on salivary levels of a selected group of pro-inflammatory cytokines for one week in a pre-and post-study design. Levels of selected cytokines were compared in whole saliva and saliva obtained using commercially available collection devices (Salivette (R) Cotton and Salivette (R) Synthetic rolls). Twenty healthy subjects drank 200 mL of a berry beverage consisting of equal parts of bilberries (Vaccinium myrtillus), black currant (Ribes nigrum), lingonberries (Vaccinium vitis-idaea), sea buckthorn (Hippophae rhamnoides) diluted with 50% water. Levels of cytokines, IL-1 beta, IL-8, IL-12 and TNF-alpha were assessed. Levels of cytokines differed between sources of collection but were highest in whole saliva. The use of cotton or synthetic rolls does not seem to be useful as a method for saliva collection and cytokine analysis. There was no significant change in the levels of selected cytokines at baseline and after intake of the berry beverage in whole stimulated saliva. There was a large inter-individual variation in cytokine levels.
Place, publisher, year, edition, pages
2016. 201-206 p.
Acta Horticulturae, ISSN 0567-7572 ; 117
IdentifiersURN: urn:nbn:se:hkr:diva-16517DOI: 10.17660/ActaHortic.2016.1117.32ISI: 000391239600032ISBN: 978-94-62611-13-9 OAI: oai:DiVA.org:hkr-16517DiVA: diva2:1070784
29th International Horticultural Congress on Horticulture - Sustaining Lives, Livelihoods and Landscapes (IHC) / 2nd International Berry Fruit Symposium - Interactions! Local and Global Berry Research and Innovation, AUG 17-22, 2014, Brisbane, AUSTRALIA