hkr.sePublikationer
Ändra sökning
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf
Alteration of neutrophil reactive oxygen species production by extracts of Devil's Claw (Harpagophytum)
Högskolan Kristianstad, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL). Swedish University of Agricultural Sciences, Balsgård.
Swedish University of Agricultural Sciences, Balsgård.
Storbritannien.
Storbritannien.
Visa övriga samt affilieringar
2016 (Engelska)Ingår i: Oxidative Medicine and Cellular Longevity, ISSN 1942-0900, E-ISSN 1942-0994, artikel-id 3841803Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Harpagophytum, Devil's Claw, is a genus of tuberiferous xerophytic plants native to southern Africa. Some of the taxa are appreciated for their medicinal effects and have been traditionally used to relieve symptoms of inflammation. The objectives of this pilot study were to investigate the antioxidant capacity and the content of total phenols, verbascoside, isoverbascoside, and selected iridoids, as well as to investigate the capacity of various Harpagophytum taxa in suppressing respiratory burst in terms of reactive oxygen species produced by human neutrophils challenged with phorbol myristate acetate (PMA), opsonised Staphylococcus aureus, and Fusobacterium nucleatum. Harpagophytum plants were classified into different taxa according to morphology, and DNA analysis was used to confirm the classification. A putative new variety of H. procumbens showed the highest degree of antioxidative capacity. Using PMA, three Harpagophytum taxa showed anti-inflammatory effects with regard to the PBS control. A putative hybrid between H. procumbens and H. zeyheri in contrast showed proinflammatory effect on the response of neutrophils to F. nucleatum in comparison with treatment with vehicle control. Harpagophytum taxa were biochemically very variable and the response in suppressing respiratory burst differed. Further studies with larger number of subjects are needed to corroborate anti-inflammatory effects of different taxa of Harpagophytum.

Ort, förlag, år, upplaga, sidor
2016. artikel-id 3841803
Nationell ämneskategori
Medicin och hälsovetenskap
Identifikatorer
URN: urn:nbn:se:hkr:diva-15696DOI: 10.1155/2016/3841803ISI: 000379477800001PubMedID: 27429708OAI: oai:DiVA.org:hkr-15696DiVA, id: diva2:952476
Tillgänglig från: 2016-08-14 Skapad: 2016-08-14 Senast uppdaterad: 2017-11-28Bibliografiskt granskad

Open Access i DiVA

fulltext(1895 kB)45 nedladdningar
Filinformation
Filnamn FULLTEXT01.pdfFilstorlek 1895 kBChecksumma SHA-512
814e00c0a3a2f506b6596bf411fba555a68defd1eb102a936652b6d46a1f017441f8ef9a2d022cab0ca24fc83ef3f6dcb335bd8838de8bca965fa38daa676e5b
Typ fulltextMimetyp application/pdf

Övriga länkar

Förlagets fulltextPubMed

Personposter BETA

Widén, Cecilia

Sök vidare i DiVA

Av författaren/redaktören
Widén, Cecilia
Av organisationen
Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL)Avdelningen för Oral hälsa och folkhälsovetenskap
I samma tidskrift
Oxidative Medicine and Cellular Longevity
Medicin och hälsovetenskap

Sök vidare utanför DiVA

GoogleGoogle Scholar
Totalt: 45 nedladdningar
Antalet nedladdningar är summan av nedladdningar för alla fulltexter. Det kan inkludera t.ex tidigare versioner som nu inte längre är tillgängliga.

doi
pubmed
urn-nbn

Altmetricpoäng

doi
pubmed
urn-nbn
Totalt: 85 träffar
RefereraExporteraLänk till posten
Permanent länk

Direktlänk
Referera
Referensformat
  • apa
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Annat format
Fler format
Språk
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Annat språk
Fler språk
Utmatningsformat
  • html
  • text
  • asciidoc
  • rtf