hkr.sePublications
Change search
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf
Extraction Efficiency of a Commercial Espresso Machine Compared to a Stainless-Steel Column Pressurized Hot Water Extraction (PHWE) System for the Determination of 23 Pharmaceuticals, Antibiotics and Hormones in Sewage Sludge
Kristianstad University, School of Education and Environment, Avdelningen för Naturvetenskap. Kristianstad University, Plattformen för molekylär analys. Kristianstad University, Faculty of Natural Science, Research environment MoLab.
Kristianstad University, School of Education and Environment, Avdelningen för Naturvetenskap. Kristianstad University, Plattformen för molekylär analys. Kristianstad University, Faculty of Natural Science, Avdelningen för miljö- och biovetenskap. Kristianstad University, Faculty of Natural Science, Research environment MoLab.ORCID iD: 0000-0003-2283-2927
2019 (English)In: Applied Sciences, E-ISSN 2076-3417, Vol. 9, no 7, article id 1509Article in journal (Refereed) Published
Abstract [en]

Two green chemistry extraction systems, an in-house stainless-steel column Pressurized Hot Water Extraction system (PHWE) and a commercially available Espresso machine were applied for analysing 23 active pharmaceutical ingredients (APIs) in sewage sludge. Final analysis was performed on UPLC-MS/MS using two different chromatographic methods: acid and basic. When analysing all 23 APIs in sewage sludge both extraction methods showed good repeatability. The PHWE method allowed for a more complete extraction of APIs that were more tightly bound to the matrix, as exemplified by much higher concentrations of e.g., ketoconazole, citalopram and ciprofloxacin. In total, 19 out of 23 investigated APIs were quantified in sewage sludge, and with a few exceptions the PHWE method was more exhaustive. Mean absolute recoveries of 7 spiked labelled APIs were lower for the PHWE method than the Espresso method. Under acid chromatographic conditions mean recoveries were 16% and 24%, respectively, but increased to 24% and 37% under basic conditions. The difference between the PHWE method and the Espresso method might be interpreted as the Espresso method giving higher extraction efficiency; however, TIC scans of extracts revealed a much higher matrix co-extraction for the PHWE method. Attempts were made to correlate occurrence of compounds in sewage sludge with chemical properties of the 23 APIs and there are strong indications that both the number of aromatic rings and the presence of a positive charge is important for the sorption processes to sewage sludge.

Place, publisher, year, edition, pages
2019. Vol. 9, no 7, article id 1509
Keywords [en]
espresso coffee machine extraction, pressurized hot water extraction, pharmaceuticals, antibiotics, hormones, sewage sludge, ion suppression, UPLC MS, MS, basic buffer
Identifiers
URN: urn:nbn:se:hkr:diva-19472DOI: 10.3390/app9071509ISI: 000466547500244OAI: oai:DiVA.org:hkr-19472DiVA, id: diva2:1330208
Available from: 2019-06-25 Created: 2019-06-25 Last updated: 2019-06-28Bibliographically approved

Open Access in DiVA

fulltext(1634 kB)14 downloads
File information
File name FULLTEXT01.pdfFile size 1634 kBChecksum SHA-512
b035a1c8e1efeadb0076c8c624098ecb21c6a82588d690d17da34cdf77ca46d4f695105a672f6a0a834af6c94fcb17f30f9016e0fb87c9ea2194b5fe17849085
Type fulltextMimetype application/pdf

Other links

Publisher's full text

Authority records BETA

Svahn, OlaBjörklund, Erland

Search in DiVA

By author/editor
Svahn, OlaBjörklund, Erland
By organisation
Avdelningen för NaturvetenskapPlattformen för molekylär analysResearch environment MoLabAvdelningen för miljö- och biovetenskap
In the same journal
Applied Sciences

Search outside of DiVA

GoogleGoogle Scholar
Total: 14 downloads
The number of downloads is the sum of all downloads of full texts. It may include eg previous versions that are now no longer available

doi
urn-nbn

Altmetric score

doi
urn-nbn
Total: 107 hits
CiteExportLink to record
Permanent link

Direct link
Cite
Citation style
  • apa
  • harvard1
  • ieee
  • modern-language-association-8th-edition
  • vancouver
  • Other style
More styles
Language
  • de-DE
  • en-GB
  • en-US
  • fi-FI
  • nn-NO
  • nn-NB
  • sv-SE
  • Other locale
More languages
Output format
  • html
  • text
  • asciidoc
  • rtf