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Measuring activities of daily living in Parkinson's disease: on a road to nowhere and back again?
Kristianstad University, Faculty of Health Science, Research Environment PRO-CARE, Patient Reported Outcomes - Clinical Assessment Research and Education. Kristianstad University, Research Platform for Collaboration for Health. Kristianstad University, Faculty of Health Science, Avdelningen för sjuksköterskeutbildningarna och integrerad hälsovetenskap.ORCID iD: 0000-0003-2174-372X
2019 (English)In: Measurement, ISSN 0263-2241, E-ISSN 1873-412X, Vol. 132, p. 109-124Article in journal (Refereed) Published
Abstract [en]

Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with increasing disability and limitations in performance of activities of daily living (ADL) despite availability of effective symptomatic therapy. Following an overview of classical test theory (CTT) and Rasch measurement theory (RMT), the case of a clinical PD trial aiming to demonstrate ADL improvements by using the ADL section (part II) of the Unified PD Rating Scale (UPDRS) to measure ADL outcomes is considered and central questions related to its validity and interpretation are addressed. It is found that while CTT did not detect any issues, RMT in combination with conceptual considerations seriously challenged the role of the UPDRS II as an ADL outcome measure. Results are discussed from historical, methodological and clinical perspectives. (C) 2018 Elsevier Ltd. All rights reserved.

Place, publisher, year, edition, pages
2019. Vol. 132, p. 109-124
Keywords [en]
Activities of daily living, Classical test theory, Outcome measurement, Parkinson's disease, Rasch measurement theory, Rating scales
National Category
Other Medical Sciences
Identifiers
URN: urn:nbn:se:hkr:diva-18849DOI: 10.1016/j.measurement.2018.09.050ISI: 000449097100011OAI: oai:DiVA.org:hkr-18849DiVA, id: diva2:1266879
Available from: 2018-11-29 Created: 2018-11-29 Last updated: 2019-01-29Bibliographically approved

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Hagell, Peter
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Research Environment PRO-CARE, Patient Reported Outcomes - Clinical Assessment Research and EducationResearch Platform for Collaboration for HealthAvdelningen för sjuksköterskeutbildningarna och integrerad hälsovetenskap
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CiteExportLink to record
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  • apa
  • harvard1
  • ieee
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  • Other style
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  • de-DE
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  • Other locale
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