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Surgical treatment of peri-implantitis lesions with or without the use of a bone substitute: a randomized clinical trial
Kristianstad University, Faculty of Health Science, Research environment Oral Health - Public Health - Quality of Life (OHAL). Kristianstad University, Faculty of Health Science, Avdelningen för oral hälsa.ORCID iD: 0000-0003-0992-2362
Kristianstad Public Dental Services.
Kristianstad University, Faculty of Health Science, Research environment Oral Health - Public Health - Quality of Life (OHAL). Kristianstad University, Faculty of Health Science, Avdelningen för oral hälsa.ORCID iD: 0000-0002-3620-5978
2018 (English)In: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 45, no 10, p. 1266-1274Article in journal (Refereed) Published
Abstract [en]

AIM: To assess whether the treatment outcome differed between surgical debridement, with or without a bone substitute.

MATERIALS AND METHODS: 41 adults with 3 or 4 wall peri-implant bone defects were enrolled in a 1-year RCT. Surgical debridement (control group), or in combination with a bone substitute (Endobon® ) (test group) was performed.

RESULTS: Radiographic evidence of defect fill (primary outcome) was only significant in the test group (p = 0.004). At year 1, no bleeding on probing (BOP) in the control and test groups were 7/20 (35%) and 10/21 (47.6%), respectively (χ2=0.67, p=0.41). Plaque scores did not differ by study group at baseline (p=0.31), or at year 1 (p=0.08). Mid-buccal soft tissue recession changes did not differ by groups (p=0.76). Successful treatment outcome (defect fill ≥ 1.0 mm, PPD values at implant ≤5 mm, no BOP, and no suppuration was identified in 1/20 (5.0%) control, and 9/21 (42.9%) test individuals (F= 7,9, p <0.01). Number needed to treat analysis identified an absolute risk reduction of 32.8% in benefit of the test procedure. (F= 7,9, p <0.01).

CONCLUSIONS: Successful treatment outcome using a bone substitute was more predictable when a composite therapeutic endpoint was considered. This article is protected by copyright. All rights reserved.

Place, publisher, year, edition, pages
2018. Vol. 45, no 10, p. 1266-1274
Keywords [en]
bone grafting, peri-implantitis, radiographs, surgical treatment
National Category
Dentistry
Identifiers
URN: urn:nbn:se:hkr:diva-18503DOI: 10.1111/jcpe.12986ISI: 000447643700012PubMedID: 30003583OAI: oai:DiVA.org:hkr-18503DiVA, id: diva2:1239271
Available from: 2018-08-16 Created: 2018-08-16 Last updated: 2018-11-01Bibliographically approved

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