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Detection of Lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes
Lunds universitet.ORCID-id: 0000-0002-9953-2829
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2012 (Engelska)Ingår i: International Journal of Probiotics and Prebiotics, ISSN 1555-1431, Vol. 7, nr 3-4, s. 135-144Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and inter-individually from <0.5 - 736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mail-in stool samples from infants should prove useful in analyzing probiotics in childhood.

Ort, förlag, år, upplaga, sidor
2012. Vol. 7, nr 3-4, s. 135-144
Nyckelord [en]
Autoimmune Diabetes; Celiac Disease; Infants; Microflora; Probiotics
Nationell ämneskategori
Endokrinologi och diabetes
Identifikatorer
URN: urn:nbn:se:hkr:diva-12766PubMedID: 25045339OAI: oai:DiVA.org:hkr-12766DiVA, id: diva2:741480
Tillgänglig från: 2014-08-28 Skapad: 2014-08-28 Senast uppdaterad: 2017-12-05Bibliografiskt granskad

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PubMedAuthor manuscript; available in PMC Jul 16, 2014

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