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Improved general and oral health in diabetic patients by an Okinawan-based Nordic diet: a pilot study
Kristianstad Central Hospital.
Högskolan Kristianstad, Fakulteten för hälsovetenskap, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL). Högskolan Kristianstad, Fakulteten för hälsovetenskap, Avdelningen för oral hälsa.
Högskolan Kristianstad, Fakulteten för hälsovetenskap, Forskningsmiljön Oral Hälsa - Allmänhälsa - Livskvalitet (OHAL). Högskolan Kristianstad, Fakulteten för hälsovetenskap, Avdelningen för oral hälsa.
Skåne University Hospital,.
Vise andre og tillknytning
2018 (engelsk)Inngår i: International Journal of Molecular Sciences, ISSN 1422-0067, E-ISSN 1422-0067, Vol. 19, nr 7, artikkel-id E1949Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

Periodontal disease, periodontitis as well as the preceding gingivitis, has been associated with both obesity and diabetes. Studies have shown that diet changes can lead to a lower incidence of such inflammation. The aim of the present case series over four weeks was to study the effects on medical and dental conditions in patients with type 2 diabetes of the consumption of the Okinawan-based Nordic Diet (OBND®). Medical and dental examinations were performed to estimate the general health and gingivitis/periodontitis. Serum cytokine levels were assessed using Luminex technology. Eight of ten study participants completed the study. All participants lost weight (p = 0.012). Six out of seven that were treated with insulin could reduce their insulin intake after two weeks with OBND®. The reduction was about 16 units which corresponds to a 34% relative reduction compared to the starting point (range 15⁻63%). Fasting blood glucose values fell (p = 0.035). Hemoglobin A1c (HbA1c) (p = 0.01), triglycerides (p = 0.05), and low-density lipoprotein (LDL) (p = 0.05) were also reduced. Bleeding on probing changed from ~28% before any dietary changes to ~13% after two weeks with OBND® (p = 0.01). The reduction in gingival bleeding was as substantial as might be expected from one session of professional tooth cleaning. Markers of inflammation were also reduced. The OBND® thus showed significant promise in alleviating the impact of diabetes on dental as well as general health.

sted, utgiver, år, opplag, sider
2018. Vol. 19, nr 7, artikkel-id E1949
Emneord [en]
bleeding on probing, clinical study, cytokines, diet, metabolic disorder, oral health
HSV kategori
Identifikatorer
URN: urn:nbn:se:hkr:diva-18369DOI: 10.3390/ijms19071949ISI: 000442807400128PubMedID: 29970834OAI: oai:DiVA.org:hkr-18369DiVA, id: diva2:1231951
Tilgjengelig fra: 2018-07-10 Laget: 2018-07-10 Sist oppdatert: 2018-09-14bibliografisk kontrollert

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