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The clinical significance of 10-m walk test standardizations in Parkinson's disease
Lund University.
Lund University.
Lund University.
Högskolan Kristianstad, Fakulteten för hälsovetenskap, Forskningsmiljön PRO-CARE, Patient Reported Outcomes - Clinical Assessment Research and Education. Högskolan Kristianstad, Forskningsplattformen för Hälsa i samverkan. Högskolan Kristianstad, Fakulteten för hälsovetenskap, Avdelningen för sjuksköterskeutbildningarna och integrerad hälsovetenskap.ORCID-id: 0000-0003-2174-372X
2018 (engelsk)Inngår i: Journal of Neurology, ISSN 0340-5354, E-ISSN 1432-1459, Vol. 265, nr 8, s. 1829-1835Artikkel i tidsskrift (Fagfellevurdert) Published
Abstract [en]

BACKGROUND: The 10-m walk test (10MWT) is a widely used measure of gait speed in Parkinson's disease (PD). However, it is unclear if different standardizations of its conduct impact test results.

AIM OF THE STUDY: We examined the clinical significance of two aspects of the standardization of the 10MWT in mild PD: static vs. dynamic start, and a single vs. repeated trials. Implications for fall prediction were also explored.

METHODS: 151 people with PD (mean age and PD duration, 68 and 4 years, respectively) completed the 10MWT in comfortable gait speed with static and dynamic start (two trials each), and gait speed (m/s) was recorded. Participants then registered all prospective falls for 6 months.

RESULTS: Absolute mean differences between outcomes from the various test conditions ranged between 0.016 and 0.040 m/s (effect sizes, 0.06-0.14) with high levels of agreement (intra-class correlation coefficients, 0.932-0.987) and small standard errors of measurement (0.032-0.076 m/s). Receiver operating characteristic curves showed similar discriminate abilities for prediction of future falls across conditions (areas under curves, 0.70-0.73). Cut-off points were estimated at 1.1-1.2 m/s.

CONCLUSIONS: Different 10MWT standardizations yield very similar results, suggesting that there is no practical need for an acceleration distance or repeated trials when conducting this test in mild PD.

sted, utgiver, år, opplag, sider
2018. Vol. 265, nr 8, s. 1829-1835
Emneord [en]
Falls, Parkinson disease, Prediction, Test standardization, The 10-m walk test
HSV kategori
Identifikatorer
URN: urn:nbn:se:hkr:diva-18202DOI: 10.1007/s00415-018-8921-9ISI: 000439926300012PubMedID: 29876762OAI: oai:DiVA.org:hkr-18202DiVA, id: diva2:1216333
Tilgjengelig fra: 2018-06-11 Laget: 2018-06-11 Sist oppdatert: 2018-08-13bibliografisk kontrollert

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