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Sättlin, Susanna
Publications (2 of 2) Show all publications
Widén, C., Erovic Ademovski, S., Karlgren-Andersson, P., Sättlin, S. & Wallin Bengtsson, V. (2017). Hälsoklinik på Tandhygienistprogrammet. Högskolepedagogisk debatt (2), 29-34
Open this publication in new window or tab >>Hälsoklinik på Tandhygienistprogrammet
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2017 (Swedish)In: Högskolepedagogisk debatt, ISSN 2000-9216, no 2, p. 29-34Article in journal (Other (popular science, discussion, etc.)) Published
Place, publisher, year, edition, pages
Kristianstad: Kristianstad University Press, 2017
National Category
Pedagogy
Identifiers
urn:nbn:se:hkr:diva-17708 (URN)
Available from: 2017-12-18 Created: 2017-12-18 Last updated: 2017-12-18Bibliographically approved
Widén, C., Holmer, H., Coleman, M., Tudor, M., Ohlsson, O., Sättlin, S., . . . Persson, G. R. (2016). Systemic inflammatory impact of periodontitis on acute coronary syndrome. Journal of Clinical Periodontology, 43(9), 713-719
Open this publication in new window or tab >>Systemic inflammatory impact of periodontitis on acute coronary syndrome
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2016 (English)In: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 43, no 9, p. 713-719Article in journal (Refereed) Published
Abstract [en]

AIM: A causative relationship between acute coronary syndrome (ACS) and periodontitis has yet to be defined. The aim of this study was to assess differences in levels of serum cytokines between individuals with or without ACS or periodontal comorbidity.

MATERIAL AND METHODS: In a case-control study, individuals with ACS (78 individuals, 10.3% females) and matching healthy controls (78 individuals, 28.2% females) were included. Medical and dental examinations were performed to diagnose ACS and periodontitis. Serum levels of cytokines were assessed using Luminex technology.

RESULTS: A diagnosis of periodontitis in the ACS and control group was diagnosed in 52.6% and 12.8% of the individuals, respectively. The unadjusted odds-ratio that individuals with ACS also had periodontitis was 7.5 (95% CI: 3.4, 16.8, p<0.001). Independent of periodontal conditions, individuals with ACS had significantly higher serum levels of IL8 (mean: 44.3 and 40.0 pg/ml) and vascular endothelial growth factor (VEGF) (mean: 82.3 and 55.3 pg/ml) than control individuals. A diagnosis of periodontitis made no difference in serum cytokine expressions.

CONCLUSION: Elevated serum levels of VEGF were associated with ACS. Serum cytokine expression in individuals with ACS is unrelated to periodontal conditions. This article is protected by copyright. All rights reserved.

Keywords
VEGF; cardiovascular disease; cytokines; hs-CRP; human; oral disease; serum
National Category
Dentistry
Identifiers
urn:nbn:se:hkr:diva-15324 (URN)10.1111/jcpe.12540 (DOI)000381034300001 ()26935585 (PubMedID)
Available from: 2016-03-08 Created: 2016-03-08 Last updated: 2017-11-30Bibliographically approved
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