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Erovic Ademovski, SeidaORCID iD iconorcid.org/0000-0002-5755-3998
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Publikationer (8 of 8) Visa alla publikationer
Erovic Ademovski, S., Mårtensson, C., Persson, R. G. & Renvert, S. (2017). The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral halitosis: a randomized clinical trial. Journal of Clinical Periodontology, 44(10), 1010-1019
Öppna denna publikation i ny flik eller fönster >>The long-term effect of a zinc acetate and chlorhexidine diacetate containing mouth rinse on intra-oral halitosis: a randomized clinical trial
2017 (Engelska)Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 44, nr 10, s. 1010-1019Artikel i tidskrift (Refereegranskat) Published
Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-16610 (URN)000417407300007 ()28727160 (PubMedID)
Tillgänglig från: 2017-03-27 Skapad: 2017-03-27 Senast uppdaterad: 2018-01-09Bibliografiskt granskad
Erovic Ademovski, S. (2017). Treatment of intra-oral halitosis. (Doctoral dissertation). Malmö university, Faculty of Odontolgy
Öppna denna publikation i ny flik eller fönster >>Treatment of intra-oral halitosis
2017 (Engelska)Doktorsavhandling, sammanläggning (Övrigt vetenskapligt)
Abstract [en]

Intra-oral  halitosis  (bad  breath)  is reported  to affect  15-83 % of the adult population. Having intra-oral halitosis is a social and psycho-logical handicap, and may cause people in the  person’s social circle to increase the physical distance or to turn their faces in another direction to avoid the unpleasant smell from the exhaled air. Such behaviours may affect the individual’s self-confidence resulting in insecurity in social and intimate relations. The oral health-related quality of life status has also been reported to be lower in individuals with halitosis. Approximately 90% of what is considered as bad breath is the result of the degradation of organic substrates (proteins) by an- aerobic bacteria of the oral cavity. Intra-oral halitosis can be  assessed using both subjective and objective methods to evaluate the subject’s exhaled air. The most common one and the one often referred to as the ”gold standard”, is the organoleptic scoring system (OLS). OLS is a subjective method  evaluating  the  strength  of halitosis in exhaled air using a scale from 0-5. One objective  method to assess the presence of volatile sulphur compounds in exhaled air is to use a sulphide monitor measuring the total sum of the volatile sulphur  compounds  (T-VSC) in exhaled  air.  The three  gases  (hydrogensulphide (H2S), methyl mercaptan (MM) and dimethyl sulphide (DMS)) in exhaled air related to intra-oral halitosis can be assessed separately using a simplified gas chromatograph. Different treatment models such as periodontal treatment, tongue scraping and rinsing with Zn ion containing products have been used to reduce intra-oralhalitosis. The  present  thesis  has  evaluated  the  efficacy of  different treatment models in the treatment of intra-oral  halitosis.

Ort, förlag, år, upplaga, sidor
Malmö university, Faculty of Odontolgy, 2017. s. 76
Serie
Doctoral dissertation in odontology ; 2017
Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-16611 (URN)978-91-7104-718-2 (ISBN)
Tillgänglig från: 2017-03-27 Skapad: 2017-03-27 Senast uppdaterad: 2017-05-09Bibliografiskt granskad
Erovic Ademovski, S., Lingström, P. & Renvert, S. (2016). The effect of different mouth rinse products on intra-oral halitosis. International Journal of Dental Hygiene, 14(2), 117-123
Öppna denna publikation i ny flik eller fönster >>The effect of different mouth rinse products on intra-oral halitosis
2016 (Engelska)Ingår i: International Journal of Dental Hygiene, ISSN 1601-5029, E-ISSN 1601-5037, Vol. 14, nr 2, s. 117-123Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

AIM: To evaluate the effect of different mouth rinses 12 h after rinsing on genuine intra-oral halitosis.

MATERIALS AND METHODS: Twenty-four adults with halitosis were included in a double-blind, crossover, randomized clinical trial. Halitosis was evaluated 12 h after rinsing with placebo and five mouth rinse products containing zinc acetate and chlorhexidine diacetate; zinc lactate, chlorhexidine and cetylpyridinium chloride; zinc acetate and chlorhexidine diacetate with reduced amounts of mint and menthol; zinc chloride and essential oil; and chlorine dioxide using the organoleptic method and a gas chromatograph. Test periods were separated by 1 week.

RESULTS: Hydrogen sulphide (H2 S), methyl mercaptan (MM) and the organoleptic scores (OLS) were significantly reduced 12 h following rinsing with all substances compared to placebo (P < 0.05). H2 S was more effectively reduced after rinsing with zinc acetate and chlorhexidine diacetate and zinc acetate and chlorhexidine diacetate with reduced amounts of mint and menthol compared to rinsing with zinc chloride and essential oil (P < 0.05), and significantly lower values of MM were obtained after rinsing with zinc acetate and chlorhexidine diacetate compared to zinc lactate, chlorhexidine and cetylpyridinium chloride (P < 0.05). The percentage effectively treated individuals (H2 S (<112 ppb), MM (<26 ppb) and OLS score <2) varied from 58% percentage (zinc acetate and chlorhexidine diacetate) to 26% (zinc chloride and essential oil).

CONCLUSION: All treatments resulted in reduction in halitosis 12 h after rinsing compared to placebo. H2 S and MM were most effectively reduced by zinc acetate and chlorhexidine diacetate.

Nyckelord
bad breath, halitosis, hydrogen sulphide, mouth rinses, volatile sulphur compounds
Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-13996 (URN)10.1111/idh.12148 (DOI)000374351500006 ()26031397 (PubMedID)
Tillgänglig från: 2015-06-04 Skapad: 2015-06-04 Senast uppdaterad: 2017-12-04Bibliografiskt granskad
Ademovski, S. E., Mårtensson, C., Persson, G. R. & Renvert, S. (2016). The effect of periodontal therapy on intra-oral halitosis: a case series. Journal of Clinical Periodontology, 43(5), 445-452
Öppna denna publikation i ny flik eller fönster >>The effect of periodontal therapy on intra-oral halitosis: a case series
2016 (Engelska)Ingår i: Journal of Clinical Periodontology, ISSN 0303-6979, E-ISSN 1600-051X, Vol. 43, nr 5, s. 445-452Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Aim: The aim of this study was to evaluate the effects of non-surgical periodontal therapy on intra-oral halitosis 3months after therapy. Material and methods: Sixty-eight adults with intra-oral halitosis were included in a case series. Intra-oral halitosis was evaluated at baseline, and at 3months after treatment using the organoleptic scores (OLS), Halimeter (R), and a gas chromatograph. Results: Significant reductions for OLS (p<0.01), total sum of volatile sulphur compounds (T-VSC) (p<0.01) and methyl mercaptan (MM) (p<0.05) values were found after treatment. Hydrogen sulphide (H2S) levels were not significantly reduced. The numbers of probing pockets 4mm, 5mm and 6mm were significantly reduced as a result of therapy (p<0.001). Bleeding on probing (BOP) and plaque indices were also significantly reduced (p<0.001). For the 34 individuals with successful periodontal treatment (BOP<20% and a 50% reduction of total pocket depth) reductions in OLS (p<0.01) and T-VSC scores (p<0.01) were found. Eleven individuals were considered effectively treated for intra-oral halitosis presenting with a T-VSC value <160ppb, a H2S value <112ppb and a MM value <26ppb. Conclusion: Non-surgical periodontal therapy resulted in reduction of OLS, MM and T-VSC values 3months after therapy. Few individuals were considered as effectively treated for intra-oral halitosis.

Nyckelord
Bad breath, hydrogen sulphide, oral halitosis, oral malodour, periodontitis, volatile sulphur compounds
Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-15484 (URN)10.1111/jcpe.12525 (DOI)000374990100007 ()26847598 (PubMedID)
Tillgänglig från: 2016-12-12 Skapad: 2016-06-07 Senast uppdaterad: 2017-11-29Bibliografiskt granskad
Erovic Ademovski, S., Persson, G. R., Winkel, E., Tangerman, A., Lingström, P. & Renvert, S. (2013). The short-term treatment effects on the microbiota at the dorsum of the tongue in intra-oral halitosis patients: a randomized clinical trial. Clinical Oral Investigations, 17(2), 463-473
Öppna denna publikation i ny flik eller fönster >>The short-term treatment effects on the microbiota at the dorsum of the tongue in intra-oral halitosis patients: a randomized clinical trial
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2013 (Engelska)Ingår i: Clinical Oral Investigations, ISSN 1432-6981, E-ISSN 1436-3771, Vol. 17, nr 2, s. 463-473Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objectives This study aims to assess the effects of rinsing with zinc- and chlorhexidine-containing mouth rinse with or without adjunct tongue scraping on volatile sulfur compounds (VSCs) in breath air, and the microbiota at the dorsum of the tongue. Material and methods A randomized single-masked controlled clinical trial with a cross-over study design over 14 days including 21 subjects was performed. Bacterial samples from the dorsum of the tongue were assayed by checkerboard DNA–DNA hybridization. Results No halitosis (identified by VSC assessments) at day 14 was identified in 12/21 subjects with active rinse alone, in 10/21with adjunct use of tongue scraper, in 1/21 for negative control rinse alone, and in 3/21 in the control and tongue scraping sequence. At day 14, significantly lower counts were identified only in the active rinse sequence ( p &lt; 0.001) for 15/78 species including , Fusobacterium sp., Porphyromonas gingivalis , Pseudomonas aeruginosa , Staphylococcus aureus , and Tannerella forsythia . A decrease in bacteria from baseline to day 14 was found in successfully treated subjects for 9/74 species including: P. gingivalis , Prevotella melaninogenica , S. aureus , and Treponema denticola . Baseline VSC scores were correlated with several bacterial species. The use of a tongue scraper combined with active rinse did not change the levels of VSC compared to rinsing alone. Conclusions VSC scores were not associated with bacterial counts in samples taken from the dorsum of the tongue. The active rinse alone containing zinc and chlorhexidine had effects on intra-oral halitosis and reduced bacterial counts of species associated with malodor. Tongue scraping provided no beneficial effects on the microbiota studied. Clinical relevance Periodontally healthy subjects with intra-oral halitosis benefit from daily rinsing with zinc- and chlorhexidine-containing mouth rinse.

Nyckelord
Bacteria, Halitosis, Mouth rinse, Tongue scraping, VSC
Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-9290 (URN)10.1007/s00784-012-0728-y (DOI)000315356700013 ()22573244 (PubMedID)
Tillgänglig från: 2012-05-16 Skapad: 2012-05-16 Senast uppdaterad: 2017-12-07Bibliografiskt granskad
Erovic Ademovski, S., Lingström, P., Winkel, E., Tangerman, A., Persson, G. R. & Renvert, S. (2012). Comparison of different treatment modalities for oral halitosis. Acta Odontologica Scandinavica, 70(3), 224-233
Öppna denna publikation i ny flik eller fönster >>Comparison of different treatment modalities for oral halitosis
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2012 (Engelska)Ingår i: Acta Odontologica Scandinavica, ISSN 0001-6357, E-ISSN 1502-3850, Vol. 70, nr 3, s. 224-233Artikel i tidskrift (Refereegranskat) Published
Abstract [en]

Objectives. To assess the effects on intra-oral halitosis by a mouth rinse containing zinc acetate (0.3%) and chlorhexidine diacetate (0.025%) with and without adjunct tongue scraping. Materials and methods. Twenty-one subjects without a diagnosis of periodontitis were randomized in a cross-over clinical trial. Organoleptic scores (OLS) were assessed to define intra-oral halitosis by total volatile sulfur compound (T-VSC) measurements and by gas chromatography. Results. Twenty-one subjects with a mean age of 45.7 years (SD: ±13.3, range: 21–66). The OLS were significantly lower following active rinse combined with tongue scraping (p < 0.001) at all time points. Immediately after, at 30 min, and at day 14, the T-VSC values were lower in the active rinse sequence than in the negative rinse sequence (p < 0.001, p < 0.001 and p < 0.05, respectively). At 30 min and at day 14, the hydrogen sulfide (H2S) and methyl mercaptan (MM) values were lower in the active rinse sequence compared to the inactive rinse sequence (p < 0.001). The inactive rinse sequence with tongue scraping reduced T-VSC at 30 min (p < 0.001) but not at 14 days. Similar reductions in T-VSC, H2S and MM were found in the active rinse sequence with or without tongue scraping. Conclusion. The use of a tongue scraper did not provide additional benefits to the active mouth rinse, but reduced OLS and tongue coating index.

Nyckelord
halitosis, mouth rinse, tongue scraper
Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-9300 (URN)10.3109/00016357.2011.635601 (DOI)000302916000008 ()22149929 (PubMedID)
Tillgänglig från: 2012-05-18 Skapad: 2012-05-18 Senast uppdaterad: 2017-12-07Bibliografiskt granskad
Renvert, S., Lingström, P. & Erovic, S. (2009). Dålig andedräkt. Tandläkartidningen, 101(7), 58-60
Öppna denna publikation i ny flik eller fönster >>Dålig andedräkt
2009 (Svenska)Ingår i: Tandläkartidningen, ISSN 0039-6982, Vol. 101, nr 7, s. 58-60Artikel i tidskrift (Övrigt vetenskapligt) Published
Abstract [sv]

Vid Högskolan i Kristianstad pågår studier för att kartlägga förekomsten av halitosis, dålig andedräkt, samt utvärdering av olika behandlingsmetoder för patienter med genuin oral halitosis.

Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-5270 (URN)
Tillgänglig från: 2009-11-05 Skapad: 2009-11-05 Senast uppdaterad: 2017-12-12Bibliografiskt granskad
Erovic, S., Lingström, P., Renvert, S., Winkel, E., Tangerman, A. & Persson, G. R. (2009). The effect on bad breath using a zinc-lacete - chlorhexidine containing mouth rinse. In: Tonetti, Maurizio, Renvert, Stefan (Ed.), Europerio 6: Stockholm, Sweden, 4-6 June 2009. Paper presented at Europerio 6 (pp. 37).
Öppna denna publikation i ny flik eller fönster >>The effect on bad breath using a zinc-lacete - chlorhexidine containing mouth rinse
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2009 (Engelska)Ingår i: Europerio 6: Stockholm, Sweden, 4-6 June 2009 / [ed] Tonetti, Maurizio, Renvert, Stefan, 2009, s. 37-Konferensbidrag, Muntlig presentation med publicerat abstract (Refereegranskat)
Abstract [en]

Background: Around 30% of the adult population has problems with Halitosis. Halitosis is caused by volatile sulfur compounds (VSC) by bacteria. The aim of this study was to evaluate the short term effect on halitosis using a zinc-lacete-chlorhexidine containing mouth rinse (SB12). Materials and methods: Twenty-five adults with halitosis were included in a clinical randomized double blind cross over study. Four test periods, each 2 weeks long separated by washout periods of 1 week was used to evaluate 4 treatments: A) SB12, B) placebo C) SB12 + tongue scraper, and D) placebo + tongue scraper. Registration of VSC using a Halimeter was done at Day 1 before rinsing, immediately after rinsing, after 30 minutes and at Day 14. Results: A reduction on VSC 30 min following treatment compared to baseline was found for substance A, C, D (P < 0.000). A reduction at Day 14 was only found for substance A (P < 0.004). Comparing treatments, significant differences was found at all time points between A and B (P < 0.01, P < 0.003, P < 0.042 respectively) and between C and B immediately after rinsing and 30 min after rinsing (P < 0.008, P < 0.003). There was non significant difference between treatment A and C or between treatments B and D. Conclusion: Rinsing with a zinc-lacete - chlorhexidine containing mouth rinse (SB12) demonstrated short term reductions of VSC. Tongue scraper alone had a limited effect on oral halitosis. The addition of tongue cleaning using a tongue scraper did not improve the results obtained by rinsing alone.

Serie
Journal of Clinical Periodontology, ISSN 0303-6979 ; 36 (Suppl. 9)
Nationell ämneskategori
Odontologi
Identifikatorer
urn:nbn:se:hkr:diva-5505 (URN)10.1111/j.1600-051X.2009.01403.x (DOI)
Konferens
Europerio 6
Tillgänglig från: 2009-12-10 Skapad: 2009-12-10 Senast uppdaterad: 2014-09-18Bibliografiskt granskad
Organisationer
Identifikatorer
ORCID-id: ORCID iD iconorcid.org/0000-0002-5755-3998

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